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Gonioscopy is always essential
Angle closure is defined by iridotrabecular contact of ≥180° (1) and the presence or development...
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Association of Blood Pressure and Retinal Nerve Fiber Layer Rates of Thinning in Patients with Moderate to Advanced Glaucoma
Objective: To investigate the influence of baseline blood pressure (BP) on retinal nerve fiber...
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Aqueous Humor Antioxidants in Glaucoma: Correlations With Subtypes, Intraocular Pressure, and Medication Use - A Prospective Study
Purpose: To investigate the correlations between aqueous humor total antioxidant capacity (TAC)...
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Care Delivery
SIG Corner Editor: Hana Abouzeid Chair: Anton B. Hommer Co-chair: Gabor Hollo Update on ongoing...
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Comparative Study of Early Safety and Effectiveness Outcomes of the PreserFlo MicroShunt with and without an Intraluminal Suture Stent
Objective: To assess the early safety and effectiveness outcomes of the PreserFlo MicroShunt with...
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Iris Crypts Could Reduce the Chance of Angle Closure: A Computational Biomechanics Study Derived From Clinical and Human Iris Data
Purpose: To investigate the effect of crypts during pupil constriction and dilation on the...
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Glaucoma drainage devices - Is the Paul glaucoma implant suitable for children with glaucoma?
Only a few studies exist on the Paul glaucoma device in children with glaucoma. Compared to Ahmed...
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Comparison of Methods to Deliver Mitomycin C in Trabeculectomy Surgery: a Systematic Review and Meta-analysis
Purpose: Compare different methods to deliver Mitomycin C (MMC) in trabeculectomy surgery....
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Aqueous Humor Antioxidants in Glaucoma: Correlations With Subtypes, Intraocular Pressure, and Medication Use - A Prospective Study
Purpose: To investigate the correlations between aqueous humor total antioxidant capacity (TAC)...
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Optic Disc Microvasculature Reduction and Visual Field Progression in Primary Open-Angle Glaucoma
Purpose: To investigate the relationship between optic disc vessel density (ODVD) reduction and...
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Consider cotton wool spots as potential triggers for (non-glaucomatous) nerve fibre bundle defects
It may be tempting to make a glaucoma diagnosis in the presence of a nerve fibre bundle defect...
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Risk Score Predicting Primary Open-Angle Glaucoma Patients With Vascular Predisposition
Purpose: We tested the hypothesis that a questionnaire-based risk score predicts the prevalence...
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Association of Rare CYP39A1 Variants With Exfoliation Syndrome Involving the Anterior Chamber of the Eye
Author(s): Genetics of Exfoliation Syndrome Partnership For a full list of authors and affiliations please visit...
April 30, 2021
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Observation or Treatment? – Implications of the Ocular Hypertension Treatment Study
Pearls Manager: Hari Jayaram The OHTS was a multicentre randomised clinical trial designed to study the effect of topical ocular hypotensive...
April 30, 2021
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My personal way to estimate whether a patient is at risk for wipeout following glaucoma surgery, is to perform a confrontation visual field with a red-topped bottle
This should be done monocularly with the bottle moved from the area of scotoma towards fixation. One must ensure that the patient is constantly...
March 31, 2021
Protrudin functions from the endoplasmic reticulum to support axon regeneration in the adult CNS
Author(s): Veselina Petrova (1), Craig S Pearson (2), Jared Ching (3,4,5), James R Tribble (6), Andrea G Solano (2), Yunfei Yang (5), Fiona M Love...
March 31, 2021
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Correlations Between Subjective Evaluation of Quality of Life, Visual Field Loss, and Performance in Simulated Activities of Daily Living in Glaucoma Patients
Author(s): Line Azoulay-Sebban (1), Zhanlin Zhao (2,3), Ariel Zenouda (1), Marco Lombardi (1,4), Emmanuel Gutman (1), Emmanuelle Brasnu (4),...
March 30, 2021
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Patient Co-operation is Essential to Achieve IOP-Lowering and Successful Outcomes
Pearls Manager: Hari Jayaram Adherence and continued usage of (“persistence”) prescribed glaucoma management is necessary to achieve sustained IOP...
March 30, 2021
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Glaucoma associated with retinal detachment
Pearls Manager: Andrew Tatham Retinal detachment is usually associated with reduction of intraocular pressure (IOP) but long standing retinal...
March 20, 2021
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Consider IOP monitoring and prophylactic treatment in patients undergoing repeat intravitreal anti-VEGF injections
Intravitreal anti-vascular endothelial growth factor (anti-VEGF) injections are now in widespread use for a plethora of retinal diseases. It is...
February 28, 2021
Anatomical Changes and Predictors of Angle Widening After Laser Peripheral Iridotomy: The Zhongshan Angle Closure Prevention Trial
Author(s): Benjamin Y Xu (1), David S Friedman (2), Paul J Foster (3), Yu Jiang (4), Anmol A Pardeshi (5), Yuzhen Jiang (4), Beatriz Munoz (6), Tin...
February 28, 2021
Longitudinal Changes in Macular Optical Coherence Tomography Angiography Metrics in Primary Open-Angle Glaucoma With High Myopia: A Prospective Study
Author(s): Fengbin Lin (1), Fei Li (1), Kai Gao (1), Wanbing He (1), Jun Zeng (1), Yu Chen (1), Meiling Chen (1), Weijing Cheng (1), Yunhe Song...
February 28, 2021
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Visual Field Progression
Pearls Manager: Andrew Tatham Visual field progression analyses may be event or trend-based. Trend analyses quantify rate of progression, usually...
February 21, 2021
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Anxiety associated with glaucoma
Pearls Manager: Andrew Tatham Diagnosis with glaucoma is a moment of anxiety for patients that can be mitigated by provision of timely support and...
February 20, 2021
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In glaucoma patients with anterior uveitis using brimonidine, one must consider `brimonidine-associated uveitis` to avoid misdiagnosis and over-treatment
Raised intraocular pressure (IOP) and secondary glaucoma due to underlying uveitis is a well-acknowledged phenomenon (1). The clinician should...
January 31, 2021
Glaucoma-Related Adverse Events at 10 Years in the Infant Aphakia Treatment Study: A Secondary Analysis of a Randomized Clinical Trial
Author(s): Sharon F Freedman (1), Allen D Beck (2), Azhar Nizam (3), Deborah K Vanderveen (4), David A Plager (5), David G Morrison (6), Carolyn D...
January 31, 2021
Peripapillary sclera exhibits a v-shaped configuration that is more pronounced in glaucoma eyes
Author(s): Xiaofei Wang (1), Tin A Tun (2,3), Monisha Esther Nongpiur (3,4), Hla M Htoon (3), Yih Chung Tham (3), Nicholas G Strouthidis (5,6), Tin...
January 31, 2021
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Anterior chamber angle imaging cannot replace gonioscopy
Pearls Manager: Andrew Tatham Anterior chamber angle imaging devices can be useful to identify the iris configuration of a narrow angle, to assess...
January 30, 2021
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Glaucoma associated with retinal detachment
Pearls Manager: Andrew Tatham Retinal detachment is usually associated with reduction of intraocular pressure (IOP) but long standing retinal...
January 30, 2021
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The side effects of timolol and other beta-adrenergic antagonists on the cardiovascular and pulmonary system in predisposed patients should not be underestimated
Since 1976 beta-adrenergic antagonists have established their role in the effective lowering of the intraocular pressure. The potential side...
December 31, 2020
Risk Factors for Visual Field Deterioration in the United Kingdom Glaucoma Treatment Study
Author(s): Panayiota Founti (1), Catey Bunce (2), Anthony P Khawaja (3), Caroline J Doré (4), Jibran Mohamed-Noriega (3), David F Garway-Heath (3),...
December 31, 2020
Metabolomic profiling of aqueous humor from glaucoma patients - The metabolomics in surgical ophthalmological patients (MISO) study
Author(s): João Barbosa Breda (1), Anca Croitor Sava (2), Uwe Himmelreich (2), Alix Somers (3), Christophe Matthys (4), Amândio Rocha Sousa (5),...
December 31, 2020
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The Mont Blanc Study: The effect of altitude on intra ocular pressure and central corneal thickness
Author(s): Carlo Bruttini (1), Alice Verticchio Vercellin (1,2,3), Catherine Klersy (4), Annalisa De Silvestri (4), Carmine Tinelli (4), Ivano Riva...
December 30, 2020
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Optical coherence tomography for glaucoma diagnosis
Pearls Manager: Andrew Tatham Optical coherence tomography (OCT) on its own does not provide a clinical diagnosis of glaucoma, just a statistical...
December 30, 2020
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Trabecular meshwork bypass surgery should be avoided if high episcleral venous pressure is suspected
The intraocular pressure lowering effect of procedures that attempt to enhance flow of aqueous into Schlemm’s canal by bypassing or cutting the...
November 30, 2020
Neuroprotection SIG
SIG Corner Editor: João Barbosa Breda Chair: Francesca Cordeiro Co-chair: Miriam Kolko The goal of this SIG is to increase ophthalmologists’...
November 30, 2020
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Minimally invasive and micro incisional glaucoma surgery
Pearls Manager: Andrew Tatham Surgical procedures that entail less tissue manipulation with the expectation of a better safety profile and quicker...
November 30, 2020