• Gonioscopy is always essential

    Angle closure is defined by iridotrabecular contact of ≥180° (1) and the presence or development of angle closure can change the treatment plan....

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    Gonioscopy is always essential

    Gonioscopy is always essential

    Angle closure is defined by iridotrabecular contact of ≥180° (1) and the presence or development...

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  • Association of Blood Pressure and Retinal Nerve Fiber Layer Rates of Thinning in Patients with Moderate to Advanced Glaucoma

    Objective: To investigate the influence of baseline blood pressure (BP) on retinal nerve fiber layer (RNFL) rates of change (RoCs) in glaucoma...

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    Association of Blood Pressure and Retinal Nerve Fiber Layer Rates of Thinning in Patients with Moderate to Advanced Glaucoma

    Association of Blood Pressure and Retinal Nerve Fiber Layer Rates of Thinning in Patients with Moderate to Advanced Glaucoma

    Objective: To investigate the influence of baseline blood pressure (BP) on retinal nerve fiber...

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  • Aqueous Humor Antioxidants in Glaucoma: Correlations With Subtypes, Intraocular Pressure, and Medication Use - A Prospective Study

    Purpose: To investigate the correlations between aqueous humor total antioxidant capacity (TAC) and glaucoma subtypes, intraocular pressure (IOP),...

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    Aqueous Humor Antioxidants in Glaucoma: Correlations With Subtypes, Intraocular Pressure, and Medication Use - A Prospective Study

    Aqueous Humor Antioxidants in Glaucoma: Correlations With Subtypes, Intraocular Pressure, and Medication Use - A Prospective Study

    Purpose: To investigate the correlations between aqueous humor total antioxidant capacity (TAC)...

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  • Care Delivery

    SIG Corner Editor: Hana Abouzeid Chair: Anton B. Hommer Co-chair: Gabor Hollo Update on ongoing projects The goal of this SIG is to keep an updated...

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    Care Delivery

    Care Delivery

    SIG Corner Editor: Hana Abouzeid Chair: Anton B. Hommer Co-chair: Gabor Hollo Update on ongoing...

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  • Comparative Study of Early Safety and Effectiveness Outcomes of the PreserFlo MicroShunt with and without an Intraluminal Suture Stent

    Objective: To assess the early safety and effectiveness outcomes of the PreserFlo MicroShunt with and without an intraluminal suture stent. Design:...

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    Comparative Study of Early Safety and Effectiveness Outcomes of the PreserFlo MicroShunt with and without an Intraluminal Suture Stent

    Comparative Study of Early Safety and Effectiveness Outcomes of the PreserFlo MicroShunt with and without an Intraluminal Suture Stent

    Objective: To assess the early safety and effectiveness outcomes of the PreserFlo MicroShunt with...

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  • Iris Crypts Could Reduce the Chance of Angle Closure: A Computational Biomechanics Study Derived From Clinical and Human Iris Data

    Purpose: To investigate the effect of crypts during pupil constriction and dilation on the potential for angle closure by performing finite element...

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    Iris Crypts Could Reduce the Chance of Angle Closure: A Computational Biomechanics Study Derived From Clinical and Human Iris Data

    Iris Crypts Could Reduce the Chance of Angle Closure: A Computational Biomechanics Study Derived From Clinical and Human Iris Data

    Purpose: To investigate the effect of crypts during pupil constriction and dilation on the...

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  • Glaucoma drainage devices - Is the Paul glaucoma implant suitable for children with glaucoma?

    Only a few studies exist on the Paul glaucoma device in children with glaucoma. Compared to Ahmed glaucoma Valve or Baerveldt implant, there is...

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    Glaucoma drainage devices - Is the Paul glaucoma implant suitable for children with glaucoma?

    Glaucoma drainage devices - Is the Paul glaucoma implant suitable for children with glaucoma?

    Only a few studies exist on the Paul glaucoma device in children with glaucoma. Compared to Ahmed...

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  • Comparison of Methods to Deliver Mitomycin C in Trabeculectomy Surgery: a Systematic Review and Meta-analysis

    Purpose: Compare different methods to deliver Mitomycin C (MMC) in trabeculectomy surgery. Clinical relevance: Knowing the best way to apply MMC...

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    Comparison of Methods to Deliver Mitomycin C in Trabeculectomy Surgery: a Systematic Review and Meta-analysis

    Comparison of Methods to Deliver Mitomycin C in Trabeculectomy Surgery: a Systematic Review and Meta-analysis

    Purpose: Compare different methods to deliver Mitomycin C (MMC) in trabeculectomy surgery....

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  • Aqueous Humor Antioxidants in Glaucoma: Correlations With Subtypes, Intraocular Pressure, and Medication Use - A Prospective Study

    Purpose: To investigate the correlations between aqueous humor total antioxidant capacity (TAC) and glaucoma subtypes, intraocular pressure (IOP),...

    Learn more...
    Aqueous Humor Antioxidants in Glaucoma: Correlations With Subtypes, Intraocular Pressure, and Medication Use - A Prospective Study

    Aqueous Humor Antioxidants in Glaucoma: Correlations With Subtypes, Intraocular Pressure, and Medication Use - A Prospective Study

    Purpose: To investigate the correlations between aqueous humor total antioxidant capacity (TAC)...

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  • Optic Disc Microvasculature Reduction and Visual Field Progression in Primary Open-Angle Glaucoma

    Purpose: To investigate the relationship between optic disc vessel density (ODVD) reduction and visual field (VF) progression in primary open-angle...

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    Optic Disc Microvasculature Reduction and Visual Field Progression in Primary Open-Angle Glaucoma

    Optic Disc Microvasculature Reduction and Visual Field Progression in Primary Open-Angle Glaucoma

    Purpose: To investigate the relationship between optic disc vessel density (ODVD) reduction and...

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  • Consider cotton wool spots as potential triggers for (non-glaucomatous) nerve fibre bundle defects

    It may be tempting to make a glaucoma diagnosis in the presence of a nerve fibre bundle defect with or without visual field defect when located in...

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    Consider cotton wool spots as potential triggers for (non-glaucomatous) nerve fibre bundle defects

    Consider cotton wool spots as potential triggers for (non-glaucomatous) nerve fibre bundle defects

    It may be tempting to make a glaucoma diagnosis in the presence of a nerve fibre bundle defect...

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  • Risk Score Predicting Primary Open-Angle Glaucoma Patients With Vascular Predisposition

    Purpose: We tested the hypothesis that a questionnaire-based risk score predicts the prevalence of patients with primary open-angle glaucoma (POAG)...

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    Risk Score Predicting Primary Open-Angle Glaucoma Patients With Vascular Predisposition

    Risk Score Predicting Primary Open-Angle Glaucoma Patients With Vascular Predisposition

    Purpose: We tested the hypothesis that a questionnaire-based risk score predicts the prevalence...

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Increased likelihood of glaucoma at the same screening intraocular pressure in subjects with pseudoexfoliation: the Thessaloniki Eye Study

Clinical paper of the month

Increased likelihood of glaucoma at the same screening intraocular pressure in subjects with pseudoexfoliation: the Thessaloniki Eye Study

Author(s): Topouzis F, Harris A, Wilson MR, Koskosas A, Founti P, Yu F, Anastasopoulos E, Pappas T, Coleman AL Department of Ophthalmology, School...

November 30, 2009

Complex antibody profile changes in an experimental autoimmune glaucoma animal model

Clinical paper of the month

Complex antibody profile changes in an experimental autoimmune glaucoma animal model

Author(s): Joachim SC, Grus FH, Kraft D, White-Farrar K, Barnes G, Barbeck M, Ghanaati S, Cao S, Li B, Wax MB Experimental Ophthalmology,...

October 31, 2009

Glaucoma medications may harm the foetus and neonate

Tip of the month

Glaucoma medications may harm the foetus and neonate

The Science behind the Tip Human data on adverse effects of glaucoma medications during pregnancy and lactation are sparse because the coincidence...

May 31, 2009

Intraocular pressure is overestimated in eyes with a thick cornea

Tip of the month

Intraocular pressure is overestimated in eyes with a thick cornea

The Science behind the Tip Variability in central corneal thickness (CCT) is a potent confounder of Goldmann applanation tonometry (GAT)(1). The...

April 30, 2009

A thin cornea is a risk factor for primary open-angle glaucoma

Tip of the month

A thin cornea is a risk factor for primary open-angle glaucoma

The Science behind the Tip Central corneal thickness (CCT) varies among individuals, the average CCT in the general population being approximately...

March 31, 2009

Intraocular pressure is underestimated in eyes with a thin cornea

Tip of the month

Intraocular pressure is underestimated in eyes with a thin cornea

The Science behind the Tip Variability in central corneal thickness (CCT) is a potent confounder of applanation tonometry techniques such as...

February 28, 2009

Visual field defects are filled-in by the brain

Tip of the month

Visual field defects are filled-in by the brain

The Science behind the Tip Contrary to long held beliefs, cortical maps in the brain are not rigid. Extensive reorganization (i.e. brain remapping)...

January 31, 2009

Pseudoexfoliation glaucoma has a strong genetic component

Tip of the month

Pseudoexfoliation glaucoma has a strong genetic component

Publishing date: December 2008 The Science behind the Tip Pseudoexfoliation or exfoliation syndrome (PEX) is the most common identifiable condition...

December 31, 2008

Chase the family of primary-open angle glaucoma patients

Tip of the month

Chase the family of primary-open angle glaucoma patients

The Science behind the Tip Various modes of screening for primary open-angle glaucoma (POAG), i.e. different combinations of tonometry and...

November 30, 2008

Intraocular pressure should be monitored after an acute episode of angle-closure

Tip of the month

Intraocular pressure should be monitored after an acute episode of angle-closure

The Science behind the Tip Treatment of acute attacks of angle-closure glaucoma induced by pupillary block is based on medical therapy aiming at...

October 31, 2008

Topical medication may accelerate cataract formation

Tip of the month

Topical medication may accelerate cataract formation

The Science behind the Tip A number of large studies have linked use of topical glaucoma medication with increased risk of nuclear cataract, the...

September 30, 2008

Closing the eyes as an alternative for nasolacrimal duct occlusion

Tip of the month

Closing the eyes as an alternative for nasolacrimal duct occlusion

The Science behind the Tip The Science behind the Tip Manual nasolacrimal occlusion after eye drop instillation is often taught to glaucoma...

June 30, 2008

There is no significant association between use of β-blockers and depression

Tip of the month

There is no significant association between use of β-blockers and depression

The Science behind the Tip The Science behind the Tip The methodological quality of early studies of the association of systemic or topical...

May 31, 2008

Trabeculectomy significantly increases the incidence of cataract formation

Tip of the month

Trabeculectomy significantly increases the incidence of cataract formation

The Science behind the Tip The Science behind the Tip It is widely acknowledged that trabeculectomy (TRAB) accelerates cataract formation. The...

April 30, 2008

Concomitant therapy with Cosopt® and Diamox® is not useful

Tip of the month

Concomitant therapy with Cosopt® and Diamox® is not useful

The Science behind the Tip Although the ß-blocker timolol and the topical carbonic anhydrase inhibitor (CAI) dorzolamide both act by decreased...

March 31, 2008

Rate of false positive answers is the only reliable reliability parameter in computerized perimetry

Tip of the month

Rate of false positive answers is the only reliable reliability parameter in computerized perimetry

The Science behind the Tip In computerized perimetry patient?s reliability is measured by 3 parameters, namely rate of false positive and false...

February 29, 2008

Normal intraocular pressure in an eye with central retinal vein occlusion does not rule out associated glaucoma

Tip of the month

Normal intraocular pressure in an eye with central retinal vein occlusion does not rule out associated glaucoma

The Science behind the Tip Ocular hypertension (OH) and primary open-angle glaucoma (POAG) are strongly associated with (hemi)central retinal vein...

January 31, 2008

Medication compliance can easily be improved

Tip of the month

Medication compliance can easily be improved

The Science behind the Tip Poor medication compliance (i.e. patients not taking their medication as directed) is a major problem in glaucoma care....

December 31, 2007

Poor visit keeping is associated with poor medication compliance

Tip of the month

Poor visit keeping is associated with poor medication compliance

The Science behind the Tip Factors associated with poor medication compliance have been determined for a number of chronic internal disorders that...

November 30, 2007

Heart failure is no contraindication to β-blocker therapy

Tip of the month

Heart failure is no contraindication to β-blocker therapy

The Science behind the Tip Contrary to long-held beliefs, ß-blockers do not aggravate heart failure and are even beneficial in the treatment of the...

October 31, 2007

Diabetes is no manifest risk factor for developing primary open-angle glaucoma

Tip of the month

Diabetes is no manifest risk factor for developing primary open-angle glaucoma

The Science behind the Tip There has been a widely held belief that diabetes increases the risk of developing primary open-angle glaucoma (POAG)....

September 30, 2007

Bilateral acute angle-closure glaucoma may occur after uneventful blepharoplasty

Tip of the month

Bilateral acute angle-closure glaucoma may occur after uneventful blepharoplasty

The Science behind the Tip Bilateral acute angle-closure glaucoma is a possible (potentially blinding) complication after uneventful eyelid...

June 30, 2007

Optic disc size can be quickly assessed at the slit lamp

Tip of the month

Optic disc size can be quickly assessed at the slit lamp

The Science behind the Tip Optic disc size influences the significance of the cup/disc ratio1,2. Disc size can be estimated using a handheld high...

May 31, 2007

Glaucoma and small optic discs: a diagnosis challenge

Tip of the month

Glaucoma and small optic discs: a diagnosis challenge

The Science behind the Tip Diagnosis and follow-up of glaucoma is challenging in eyes with small optic discs (height < 1.2 mm or surface area...

April 30, 2007

Tracking structural abnormalities is more important in early glaucoma than at the end of the disease

Tip of the month

Tracking structural abnormalities is more important in early glaucoma than at the end of the disease

The Science behind the Tip Diagnosing glaucoma and documenting progression at an early stage of the disease is a key thing to successful glaucoma...

March 31, 2007