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The scleral spur
The scleral spur is a ring-shaped structure, primarily collagen with 5% elastin (1), providing...
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Neuroprotection in Glaucoma: Investigational, Complementary to IOP-Lowering
Tip: Neuroprotection in glaucoma is investigational and may be considered only as an adjunct,...
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Evaluating High Intraocular Pressure Criteria for Failure in Glaucoma Surgery: Impact on Estimated Success and Visual Field Rates
Purpose: Review high intraocular pressure (IOP) thresholds used as failure criteria in glaucoma...
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Gonioscopy is always essential
Angle closure is defined by iridotrabecular contact of ≥180° (1) and the presence or development...
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Association of Blood Pressure and Retinal Nerve Fiber Layer Rates of Thinning in Patients with Moderate to Advanced Glaucoma
Objective: To investigate the influence of baseline blood pressure (BP) on retinal nerve fiber...
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Aqueous Humor Antioxidants in Glaucoma: Correlations With Subtypes, Intraocular Pressure, and Medication Use - A Prospective Study
Purpose: To investigate the correlations between aqueous humor total antioxidant capacity (TAC)...
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Care Delivery
SIG Corner Editor: Hana Abouzeid Chair: Anton B. Hommer Co-chair: Gabor Hollo Update on ongoing...
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Comparative Study of Early Safety and Effectiveness Outcomes of the PreserFlo MicroShunt with and without an Intraluminal Suture Stent
Objective: To assess the early safety and effectiveness outcomes of the PreserFlo MicroShunt with...
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Iris Crypts Could Reduce the Chance of Angle Closure: A Computational Biomechanics Study Derived From Clinical and Human Iris Data
Purpose: To investigate the effect of crypts during pupil constriction and dilation on the...
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Glaucoma drainage devices - Is the Paul glaucoma implant suitable for children with glaucoma?
Only a few studies exist on the Paul glaucoma device in children with glaucoma. Compared to Ahmed...
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Comparison of Methods to Deliver Mitomycin C in Trabeculectomy Surgery: a Systematic Review and Meta-analysis
Purpose: Compare different methods to deliver Mitomycin C (MMC) in trabeculectomy surgery....
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Aqueous Humor Antioxidants in Glaucoma: Correlations With Subtypes, Intraocular Pressure, and Medication Use - A Prospective Study
Purpose: To investigate the correlations between aqueous humor total antioxidant capacity (TAC)...
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Trabecular meshwork bypass surgery should be avoided if high episcleral venous pressure is suspected
The intraocular pressure lowering effect of procedures that attempt to enhance flow of aqueous into Schlemm’s canal by bypassing or cutting the...
November 30, 2020
Neuroprotection SIG
SIG Corner Editor: João Barbosa Breda Chair: Francesca Cordeiro Co-chair: Miriam Kolko The goal of this SIG is to increase ophthalmologists’...
November 30, 2020
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Minimally invasive and micro incisional glaucoma surgery
Pearls Manager: Andrew Tatham Surgical procedures that entail less tissue manipulation with the expectation of a better safety profile and quicker...
November 30, 2020
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Haemodialysis can cause an acute rise in intraocular pressure
Haemodialysis (HD) can reportedly induce a sudden rise in intraocular pressure (IOP) in patients with neovascular (NVG) (1) and pseudo-exfoliative...
October 31, 2020
Longitudinal Macular Ganglion Cell-Inner Plexiform Layer Measurements to Detect Glaucoma Progression in High Myopia
Author(s): Joong Won Shin (1), Min Kyung Song (1), Kyung Rim Sung (2) 1 Department of Ophthalmology, College of Medicine, University of Ulsan, Asan...
October 31, 2020
Lamina Cribrosa Capillaries Straighten as Intraocular Pressure Increases
Author(s): Bryn L Brazile (1), Bin Yang (1,2), Susannah Waxman (1) , Po Lam (1), Andrew P Voorhees (1), Yi Hua (1), Ralitsa T Loewen (1), Nils A...
October 31, 2020
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Malignant glaucoma
Pearls Manager: Andrew Tatham Malignant glaucoma or aqueous misdirection is a rare type of secondary angle closure glaucoma most commonly...
October 20, 2020
Angle Closure - Relevant breakthroughs in this field
2.1 Should laser peripheral iridotomy (LPI) be performed in primary angle-closure suspect (PACS) patients? Last year we covered the EAGLE and ZAP...
October 01, 2020
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Glaucoma progression: watch out the fellow, non-progressing eye
In clinical practice, the detection of visual field progression in one eye usually leads to management modifications in that eye. Less attention is...
September 30, 2020
Cardiovascular Disease may predict structural and functional progression in early glaucoma
Author(s): Henry Marshall (1), Sean Mullany (2), Ayub Qassim (2), Mark Hassall (2), Owen Siggs (2), Bronwyn Ridge (2), Thi Nguyen (2), Mona...
September 30, 2020
Association of Glaucoma Risk Genes with Retinal Nerve Fiber Layer in a Multi-ethnic Asian Population: The Singapore Epidemiology of Eye Diseases Study
Author(s): Xiaoran Chai (1,2,3), Kok Yao Low (1,4), Yih Chung Tham (1), Miao Li Chee (1), Sahil Thakur (1), Liang Zhang (1), Nicholas Y Tan (1),...
September 30, 2020
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Mutations in SPATA13/ASEF2 Cause Primary Angle Closure Glaucoma
Author(s): Naushin H Waseem (1), Sancy Low (2,3,4), Amna Z Shah (3), Deepa Avisetti (5), Pia Ostergaard (6), Michael Simpson (7), Katarzyna A...
September 30, 2020
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Optimising eye drop instillation
Pearls Manager: Andrew Tatham When two eye drops are instilled 30 seconds apart, almost 50% of the first drug will be washed out. It is recommended...
September 30, 2020
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Take care not to miss glaucomatous cupping in patients with small discs!
The Science behind the Tip The diagnosis of glaucoma can be missed in patients with small optic discs (1). In such patients, relative crowding of...
July 31, 2020
Longitudinal Macular Structure–Function Relationships in Glaucoma
Author(s): Vahid Mohammadzadeh (1), Alessandro Rabiolo (2), Qiang Fu (3), Esteban Morales (1), Anne L Coleman (1), Simon K Law (1), Joseph Caprioli...
July 31, 2020
Efficacy for Differentiating Nonglaucomatous Versus Glaucomatous Optic Neuropathy Using Deep Learning Systems
Author(s): Hee Kyung Yang (1), Young Jae Kim (2), Jae Yun Sung (1), Dong Hyun Kim (1), Kwang Gi Kim (3), Jeong-Min Hwang (4) 1 Department of...
July 31, 2020
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The Collaborative Normal Tension Glaucoma Study (CNTGS)
Pearls Manager: Andrew Tatham The CNTGS compared treatment versus no treatment in patients with normal tension glaucoma who had verified...
July 30, 2020
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Ask your glaucoma patients about mobility rather than vision
The Science behind the Tip Self-reported visual disability in glaucoma which correlates with level of visual field loss includes bumping into...
June 30, 2020
Visual Field Outcomes from the Multicenter, Randomized Controlled Laser in Glaucoma and Ocular Hypertension Trial
Author(s): David M.Wright (1,2), Evgenia Konstantakopoulou (3,4,5), Giovanni Montesano (6), Neil Nathwani (3), Anurag Garg (3), David Garway-Heath...
June 30, 2020
Using Deep Learning to Automate Goldmann Applanation Tonometry Readings
Author(s): Ted Spaide (1), Yue Wu (1), Ryan T Yanagihara (1), Shu Feng (1), Omar Ghabra (1), Jonathan S Yi (1), Philip P Chen (1), Francy Moses...
June 30, 2020
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Wound healing is one of the main determinants of long-term intraocular pressure control after filtering surgery
Pearls Manager: Andrew Tatham Risk factors for conjunctival scarring include young age, African ancestry, inflammatory eye disease, long-term...
June 18, 2020
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Glaucoma patients on topical treatment should be routinely checked for signs of ocular surface disease even if they are asymptomatic
The Science behind the Tip The prevalence of ocular surface disease is significantly higher in glaucoma patients (1). While generally accepted that...
May 31, 2020
Franz Fankhauser: the father of the automated perimeter
Author(s): Gloor BP Zürich, Switzerland. Franz Fankhauser is known as the father of automated perimetry and of the q-switched Nd:YAG laser knife....
May 31, 2020
Circadian Regulation of IOP Rhythm by Dual Pathways of Glucocorticoids and the Sympathetic Nervous System
Author(s): Ikegami K, Shigeyoshi Y, Masubuchi S PURPOSE: Elevated IOP can cause the development of glaucoma. The circadian rhythm of IOP depends on...
May 31, 2020
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Individualized glaucoma treatment
Pearls Manager: Andrew Tatham Individualized glaucoma treatment aims at providing glaucoma management tailored to the individual needs of the...
May 30, 2020