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F4H5 Alleviates Increased Outflow Resistance Induced by Emulsified Silicone Oil In Vitro
Purpose: The purpose of this study was to investigate the effect of emulsified silicone oil on...
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The scleral spur
The scleral spur is a ring-shaped structure, primarily collagen with 5% elastin (1), providing...
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Neuroprotection in Glaucoma: Investigational, Complementary to IOP-Lowering
Tip: Neuroprotection in glaucoma is investigational and may be considered only as an adjunct,...
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Evaluating High Intraocular Pressure Criteria for Failure in Glaucoma Surgery: Impact on Estimated Success and Visual Field Rates
Purpose: Review high intraocular pressure (IOP) thresholds used as failure criteria in glaucoma...
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Gonioscopy is always essential
Angle closure is defined by iridotrabecular contact of ≥180° (1) and the presence or development...
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Association of Blood Pressure and Retinal Nerve Fiber Layer Rates of Thinning in Patients with Moderate to Advanced Glaucoma
Objective: To investigate the influence of baseline blood pressure (BP) on retinal nerve fiber...
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Aqueous Humor Antioxidants in Glaucoma: Correlations With Subtypes, Intraocular Pressure, and Medication Use - A Prospective Study
Purpose: To investigate the correlations between aqueous humor total antioxidant capacity (TAC)...
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Care Delivery
SIG Corner Editor: Hana Abouzeid Chair: Anton B. Hommer Co-chair: Gabor Hollo Update on ongoing...
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Comparative Study of Early Safety and Effectiveness Outcomes of the PreserFlo MicroShunt with and without an Intraluminal Suture Stent
Objective: To assess the early safety and effectiveness outcomes of the PreserFlo MicroShunt with...
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Iris Crypts Could Reduce the Chance of Angle Closure: A Computational Biomechanics Study Derived From Clinical and Human Iris Data
Purpose: To investigate the effect of crypts during pupil constriction and dilation on the...
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Glaucoma drainage devices - Is the Paul glaucoma implant suitable for children with glaucoma?
Only a few studies exist on the Paul glaucoma device in children with glaucoma. Compared to Ahmed...
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Comparison of Methods to Deliver Mitomycin C in Trabeculectomy Surgery: a Systematic Review and Meta-analysis
Purpose: Compare different methods to deliver Mitomycin C (MMC) in trabeculectomy surgery....
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Activated retinal glia mediated axon regeneration in experimental glaucoma
Author(s): Lorber B, Guidi A, Fawcett JW, Martin KR. Centre for Brain Repair, University of Cambridge, Cambridge, UK. Glaucoma, a leading cause of...
September 30, 2011
During Glaucoma, {alpha}2-Macroglobulin Accumulates in Aqueous Humor and Binds to Nerve Growth Factor, Neutralizing Neuroprotection
Author(s): Bai Y, Sivori D, Woo SB, Neet KE, Lerner SF, Saragovi HU Lady Davis Institute-Jewish General Hospital PURPOSE: Glaucoma is an optic...
August 31, 2011
Ex vivo optical coherence tomography imaging of collector channels with a scanning endoscopic probe
Author(s): Ren J, Gille HK, Wu J, Yang C. Departments of Electrical Engineering and. PURPOSE: To achieve high-fidelity optical coherence tomography...
July 31, 2011
Distortion of axonal cytoskeleton: an early sign of glaucomatous damage
Author(s): Huang X, Kong W, Zhou Y, Gregori G. PURPOSE: Glaucoma damages the retinal nerve fiber layer (RNFL). The purpose of this study was to...
June 30, 2011
Elastic modulus determination of normal and glaucomatous human trabecular meshwork
Author(s): Last JA, Pan T, Ding Y, Reilly CM, Keller K, Acott TS, Fautsch MP, Murphy CJ, Russell P. Department of Chemical and Biological...
May 31, 2011
Early Gene Expression Changes in the Retinal Ganglion Cell Layer of a Rat Glaucoma Model
Author(s): Guo Y, Johnson EC, Cepurna WO, Dyck J, Doser T, Morrison JC. Ophthalmology, Oregon Health & Sciences University, Portland, United...
April 30, 2011
Imaging the aqueous humor outflow pathway in human eyes by three-dimensional micro-computed tomography (3D micro-CT)
Author(s): Hann CR, Bentley MD, Vercnocke A, Ritman EL, Fautsch MP Department of Ophthalmology, Mayo Clinic, 200 First Street SW, Rochester, MN...
March 31, 2011
Evidence for a role of angiopoietin-like 7 (ANGPTL7) in extracellular matrix formation of the human trabecular meshwork: implications for glaucoma
Author(s): Comes N, Buie LK, Borrás T. Department of Ophthalmology, University of North Carolina School of Medicine, Chapel Hill, NC, USA. The...
February 28, 2011
Reversal of retinal ganglion cell dysfunction after surgical reduction of intraocular pressure
Author(s): Sehi M, Grewal DS, Goodkin ML, Greenfield DS. Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami Miller...
January 31, 2011
Qualitative and quantitative morphologic changes in the vasculature and extracellular matrix of the prelaminar optic nerve head in eyes with POAG
Author(s): Tektas OY, Lütjen-Drecoll E, Scholz M Institute of Anatomy II, University of Erlangen-Nuremberg, Erlangen, Germany....
November 30, 2010
Functional MRI signal changes in primary visual cortex corresponding to the central normal visual field of patients with primary open-angle glaucoma
Author(s): Qing G, Zhang S, Wang B, Wang N Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology...
October 31, 2010
Current approaches and future prospects for stem cell rescue and regeneration of the retina and optic nerve
Author(s): Dahlmann-Noor A, Vijay S, Jayaram H, Limb A, Khaw PT. The 3 most common causes of visual impairment and legal blindness in developed...
September 30, 2010
Genome-wide association study of normal tension glaucoma: common variants in SRBD1 and ELOVL5 contribute to disease susceptibility
Author(s): Writing Committee fot the Normal Tension Glaucoma Genetic Study Group of Japan Glaucoma Society, Meguro A, Inoko H, Ota M, Mizuki N,...
August 31, 2010
Mitochondrial damage in the trabecular meshwork of patients with glaucoma
Author(s): Izzotti A, Saccà SC, Longobardi M, Cartiglia C. Department of Health Sciences, University of Genoa, Genoa, Italy. izzotti@unige.it...
July 31, 2010
Metabolic vulnerability disposes retinal ganglion cell axons to dysfunction in a model of glaucomatous degeneration
Author(s): Baltan S, Inman DM, Danilov CA, Morrison RS, Calkins DJ, Horner PJ. We tested the hypothesis that glaucoma disrupts electrophysiological...
June 30, 2010
Neuroprotective Effects of Intravitreal Mesenchymal Stem Cell Transplantation in Experimental Glaucoma
Author(s): Thomas V. Johnson(1,2,3) Natalie D. Bull(1,2) David P. Hunt(1), Nephtali Marina(1), Stanislav I. Tomarev(3), Keith R. Martin(1) Centre...
May 31, 2010
Episcleral Venous Pressure Responses to Topical Nitroprusside and N-Nitro-L-arginine Methyl Ester.
Author(s): Zamora DO, Kiel JW. Department of Ophthalmology, University of Texas Health Science Center, San Antonio, Texas. PURPOSE: To determine...
March 31, 2010
Hemoglobin expression and regulation in glaucoma: insights into retinal ganglion cell oxygenation.
Author(s): Tezel G, Yang X, Luo C, Cai J, Kain AD, Powell DW, Kuehn MH, Pierce WM Department of Ophthalmology and Visual Sciences, University of...
February 28, 2010
Ocular hypertension impairs optic nerve axonal transport leading to progressive retinal ganglion cell degeneration
Author(s): Salinas-Navarro M, Alarcón-Martínez L, Valiente-Soriano FJ, Jiménez-López M, Mayor-Torroglosa S, Avilés-Trigueros M, Villegas-Pérez MP,...
January 31, 2010