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Not every ring scotoma is due to glaucoma
In advanced stages of glaucoma, patients may present with an annular scotoma, also known as ring...
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Relationship between Blood Pressure and Rates of Glaucomatous Visual Field Progression
Purpose: To examine the relationship between systemic arterial blood pressure (BP) and the rate...
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Comparison of Outcomes of Deep Sclerectomy, Canaloplasty, and Viscocanaloplasty: A Multi-Centred Study
Prcis: Deep sclerectomy (DS) and canaloplasty provide better intraocular pressure (IOP) control...
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Macular Oxygen Saturation in Glaucoma Using Retinal Oximetry of Visible Light Optical Coherence Tomography: A Pilot Study
Purpose: A cross-sectional pilot study to compare macular oxygen saturation (sO2) and associated...
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Childhood Glaucoma
SIG Corner Editor: Hana Abouzeid Chair: Esther Hoffmann Co-chair: Zeynep Aktas Childhood glaucoma...
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Avoid premature removal of the intraluminal suture in glaucoma drainage devices to minimize the risk of hypotony
While prolene suture removal is an effective method for reducing IOP at the slit-lamp, removing...
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Biomechanics-Function in Glaucoma: Improved Visual Field Predictions from IOP-Induced Neural Strains
Purpose: (1) To assess whether neural tissue structure and biomechanics could predict functional...
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Validation of a Visual Field Prediction Tool for Glaucoma: A Multicenter Study Involving Patients With Glaucoma in the United Kingdom
Purpose: A previously developed machine-learning approach with Kalman filtering technology...
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Fatal beauty: which cosmetics are your glaucoma patients using?
Colorism refers to the difference in social treatment between light-skinned and dark-skinned...
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The relationship between multiple deprivation and severity of glaucoma at diagnosis
BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with...
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Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients
Vitreous traction can cause artifacts that may obscure RNFL thinning, potentially leading to...
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Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis
Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee...
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Reduction in Blood Glutathione Levels Occurs Similarly in Patients with Primary-Open Angle or Normal Tension Glaucoma
Author(s): Gherghel D, Mroczkowska S, Qin L Vascular Research Laboratory, Ophthalmic Research Group, Aston University, School of Life and Health...
May 31, 2013
Tissue engineering the retinal ganglion cell nerve fiber layer
Author(s): Kador KE, Montero RB, Venugopalan P, Hertz J, Zindell AN, Valenzuela DA, Uddin MS, Lavik EB, Muller KJ, Andreopoulos FM, Goldberg JL...
April 30, 2013
Discovery of novel human aquaporin-1 blockers
Author(s): Seeliger D, Zapater C, Krenc D, Haddoub R, Flitsch S, Beitz E, Cerdà J, de Groot BL. Human aquaporin-1 (hAQP1) is a water channel found...
March 31, 2013
Protective effect of lipoic acid against oxidative stress is mediated by Keap1/Nrf2-dependent heme oxygenase-1 induction in the RGC-5 cell line
Author(s): Koriyama Y, Nakayama Y, Matsugo S, Kato S. Department of Molecular Neurobiology, Graduate School of Medicine. Electronic address:...
February 28, 2013
A new safety concern for glaucoma treatment demonstrated by mass spectrometry imaging of benzalkonium chloride distribution in the eye, an experimental study in rabbits
Author(s): Brignole-Baudouin F, Desbenoit N, Hamm G, Liang H, Both JP, Brunelle A, Fournier I, Guerineau V, Legouffe R, Stauber J, Touboul D,...
January 31, 2013
Dorsomedial/Perifornical hypothalamic stimulation increases intraocular pressure, intracranial pressure, and the translaminar pressure gradient
Author(s): Samuels BC, Hammes NM, Johnson PL, Shekhar A, McKinnon SJ, Allingham RR Eugene and Marilyn Glick Eye Institute, the. PURPOSE:...
December 31, 2012
Genome-wide association analyses identify three new susceptibility loci for primary angle closure glaucoma
Author(s): Vithana EN, Khor CC, Qiao C, Nongpiur ME, George R, Chen LJ, Do T, Abu-Amero K, Huang CK, Low S, Tajudin LS, Perera SA, Cheng CY, Xu L,...
November 30, 2012
Intraocular pressure magnitude and variability as predictors of rates of structural change in non-human primate experimental glaucoma
Author(s): Gardiner SK, Fortune B, Wang L, Downs JC, Burgoyne CF Devers Eye Institute, Legacy Health, 1225 NE 2nd Ave., Portland, OR 97232, USA....
October 31, 2012
siRNA Silencing of Gene Expression in Trabecular Meshwork: RhoA siRNA Reduces IOP in Mice
Author(s): Liu Q, Wu K, Qiu X, Yang Y, Lin X, Yu M Few reports described efficient transfection in the trabecular meshwork (TM) in vivo. In the...
September 30, 2012
Structural and functional abnormalities of retinal ganglion cells measured in vivo at the onset of optic nerve head surface change in experimental glaucoma
Author(s): Fortune B, Burgoyne CF, Cull GA, Reynaud J, Wang L. Devers Eye Institute, Discoveries in Sight Research Laboratories, Legacy Research...
July 31, 2012
IOP induces upregulation of GFAP and MHC-II and microglia reactivity in mice retina contralateral to experimental glaucoma
Author(s): Gallego BI, Salazar JJ, de Hoz R, Rojas B, Ramírez AI, Salinas-Navarro M, Ortín-Martínez A, Valiente-Soriano FJ, Avilés-Trigueros M,...
June 30, 2012
JNK2 and JNK3 are major regulators of axonal injury-induced retinal ganglion cell death
Author(s): Fernandes KA, Harder JM, Fornarola LB, Freeman RS, Clark AF, Pang IH, John SW, Libby RT. Flaum Eye Institute, University of Rochester...
May 31, 2012
Cerebrospinal fluid exchange in the optic nerve in normal-tension glaucoma
Author(s): Killer HE, Miller NR, Flammer J, Meyer P, Weinreb RN, Remonda L, Jaggi GP. Kantonsspital Aarau, CH-5001 Aarau, Switzerland;...
April 30, 2012
Multipotent Stem Cells from Trabecular Meshwork Become Phagocytic TM cells
Author(s): Du Y, Roh DS, Mann MM, Funderburgh ML, Funderburgh JL, Schuman JS. UPMC Eye Center, Ophthalmology and Visual Science Research Center,...
March 31, 2012
A New Approach to Assess Intracranial White Matter Abnormalities in Glaucoma Patients Changes of Fractional Anisotropy Detected by 3T Diffusion Tensor Imaging
Author(s): Engelhorn T, Michelson G, Waerntges S, Hempel S, El-Rafei A, Struffert T, Doerfler A. Department of Neuroradiology, University of...
February 29, 2012
Vision deficits precede structural losses in a mouse model of mitochondrial dysfunction and progressive retinal degeneration
Author(s): Laliberté AM, Macpherson TC, Micks T, Yan A, Hill KA Department of Biology, The University of Western Ontario, London, Ontario N6A 5B7,...
January 31, 2012
IOP-Induced Lamina Cribrosa Deformation and Scleral Canal Expansion: Independent or Related?
Author(s): Sigal IA, Yang H, Roberts MD, Grimm JL, Burgoyne CF, Demirel S, Downs JC. Ocular Biomechanics Laboratory. PURPOSE: To study the...
December 31, 2011
Genetic architecture of open angle glaucoma and related determinants
Author(s): Ramdas WD, Amin N, van Koolwijk LM, Janssens AC, Demirkan A, de Jong PT, Aulchenko YS, Wolfs RC, Hofman A, Rivadeneira F, Uitterlinden...
December 31, 2011
Identification of a Novel Locus for Autosomal Dominant Primary Open Angle Glaucoma on 4q35.1-q35.2.
Author(s): Porter LF, Urquhart JE, O'Donoghue E, Spencer AF, Wade EM, Manson FD, Black GC. School of Biomedicine, The University of Manchester,...
November 30, 2011
24-Hour IOP Telemetry in the Non-human Primate: Implant System Performance and Initial Characterization of IOP At Multiple Timescales
Author(s): Downs JC, Burgoyne CF, Seigfreid WP, Reynaud JF, Strouthidis NG, Sallee V. Ocular Biomechanics Laboratory, Devers Eye Institute,...
October 31, 2011
Activated retinal glia mediated axon regeneration in experimental glaucoma
Author(s): Lorber B, Guidi A, Fawcett JW, Martin KR. Centre for Brain Repair, University of Cambridge, Cambridge, UK. Glaucoma, a leading cause of...
September 30, 2011
During Glaucoma, {alpha}2-Macroglobulin Accumulates in Aqueous Humor and Binds to Nerve Growth Factor, Neutralizing Neuroprotection
Author(s): Bai Y, Sivori D, Woo SB, Neet KE, Lerner SF, Saragovi HU Lady Davis Institute-Jewish General Hospital PURPOSE: Glaucoma is an optic...
August 31, 2011
Ex vivo optical coherence tomography imaging of collector channels with a scanning endoscopic probe
Author(s): Ren J, Gille HK, Wu J, Yang C. Departments of Electrical Engineering and. PURPOSE: To achieve high-fidelity optical coherence tomography...
July 31, 2011
Distortion of axonal cytoskeleton: an early sign of glaucomatous damage
Author(s): Huang X, Kong W, Zhou Y, Gregori G. PURPOSE: Glaucoma damages the retinal nerve fiber layer (RNFL). The purpose of this study was to...
June 30, 2011
Elastic modulus determination of normal and glaucomatous human trabecular meshwork
Author(s): Last JA, Pan T, Ding Y, Reilly CM, Keller K, Acott TS, Fautsch MP, Murphy CJ, Russell P. Department of Chemical and Biological...
May 31, 2011