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Not every ring scotoma is due to glaucoma
In advanced stages of glaucoma, patients may present with an annular scotoma, also known as ring...
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Relationship between Blood Pressure and Rates of Glaucomatous Visual Field Progression
Purpose: To examine the relationship between systemic arterial blood pressure (BP) and the rate...
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Comparison of Outcomes of Deep Sclerectomy, Canaloplasty, and Viscocanaloplasty: A Multi-Centred Study
Prcis: Deep sclerectomy (DS) and canaloplasty provide better intraocular pressure (IOP) control...
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Macular Oxygen Saturation in Glaucoma Using Retinal Oximetry of Visible Light Optical Coherence Tomography: A Pilot Study
Purpose: A cross-sectional pilot study to compare macular oxygen saturation (sO2) and associated...
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Childhood Glaucoma
SIG Corner Editor: Hana Abouzeid Chair: Esther Hoffmann Co-chair: Zeynep Aktas Childhood glaucoma...
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Avoid premature removal of the intraluminal suture in glaucoma drainage devices to minimize the risk of hypotony
While prolene suture removal is an effective method for reducing IOP at the slit-lamp, removing...
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Biomechanics-Function in Glaucoma: Improved Visual Field Predictions from IOP-Induced Neural Strains
Purpose: (1) To assess whether neural tissue structure and biomechanics could predict functional...
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Validation of a Visual Field Prediction Tool for Glaucoma: A Multicenter Study Involving Patients With Glaucoma in the United Kingdom
Purpose: A previously developed machine-learning approach with Kalman filtering technology...
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Fatal beauty: which cosmetics are your glaucoma patients using?
Colorism refers to the difference in social treatment between light-skinned and dark-skinned...
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The relationship between multiple deprivation and severity of glaucoma at diagnosis
BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with...
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Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients
Vitreous traction can cause artifacts that may obscure RNFL thinning, potentially leading to...
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Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis
Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee...
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Soluble Tumor Necrosis Factor Alpha Promotes Retinal Ganglion Cell Death in Glaucoma via Calcium-Permeable AMPA Receptor Activation
Author(s): Cueva Vargas JL (1), Osswald IK (2), Unsain N (3), Aurousseau MR (2), Barker PA (3), Bowie D (2), Di Polo A (4) 1 Department of...
October 31, 2015
In vivo imaging of axonal transport of mitochondria in the diseased and aged mammalian CNS
Author(s): Takihara Y (1), Inatani M (2), Eto K (3), Inoue T (4), Kreymerman A (5), Miyake S (6), Ueno S (7), Nagaya M (7), Nakanishi A (7), Iwao K...
September 30, 2015
Capsid Mutated Adeno-Associated Virus Delivered to the Anterior Chamber Results in Efficient Transduction of Trabecular Meshwork in Mouse and Rat
Author(s): Bogner B (1), Boye SL (2), Min SH (2), Peterson JJ (2), Ruan Q (2), Zhang Z (1), Reitsamer HA (1), Hauswirth WW (2), Boye SE (2) 1...
July 31, 2015
In vivo dynamics of retinal microglial activation during neurodegeneration: confocal ophthalmoscopic imaging and cell morphometry in mouse glaucoma
Author(s): Bosco A (1), Romero CO (2), Ambati BK (3), Vetter ML (2) 1 Department of Neurobiology & Anatomy, University of Utah;...
June 30, 2015
A common variant mapping to CACNA1A is associated with susceptibility to exfoliation syndrome
Author(s): Aung T, Ozaki M, Mizoguchi T, Allingham RR, Li Z, Haripriya A, Nakano S, Uebe S, Harder JM, Chan AS, Lee MC, Burdon KP, Astakhov YS,...
April 30, 2015
Characteristic patterns of dendritic remodeling in early-stage glaucoma: evidence from genetically identified retinal ganglion cell types
Author(s): El-Danaf RN (1), Huberman AD (2) 1 Department of Neurosciences, Neurobiology Section in the Division of Biological Sciences, and...
March 31, 2015
Neuroprotective effects of transcription factor Brn3b in an ocular hypertension rat model of glaucoma
Author(s): Stankowska DL (1), Minton AZ (2), Rutledge MD (3), Mueller BH (4), Phatak NR (5), He S (6), Ma HY (7), Forster MJ (8), Yorio T (9),...
February 28, 2015
Cumulative mtDNA damage and mutations contribute to the progressive loss of RGCs in a rat model of glaucoma
Author(s): Wu J (1), Zhang S (1), Nickerson JM (2), Gao F (3), Sun Z (4), Chen X (3), Zhang S (3), Zhang R (3), Gao F (3), Chen J (3), Luo Y (3),...
January 31, 2015
Direct optic nerve sheath (DONS) application of Schwann cells prolongs retinal ganglion cell survival in vivo
Author(s): Guo L(1), Davis B(1), Nizari S(1), Normando EM(2), Shi H(3), Galvao J(1), Turner L(1), Shi J(4), Clements M(5), Parrinello S(5),...
December 31, 2014
Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process
Author(s): Springelkamp H, Höhn R, Mishra A, Hysi PG, Khor CC, Loomis SJ, Bailey JN, Gibson J, Thorleifsson G, Janssen SF, Luo X, Ramdas WD,...
November 30, 2014
Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma
Author(s): Hysi PG(1), Cheng CY(2), Springelkamp H(3), Macgregor S(4), Bailey JN(5), Wojciechowski R(6), Vitart V(7), Nag A(8), Hewitt AW(9), Höhn...
October 31, 2014
Artemin augments survival and axon regeneration in axotomized retinal ganglion cells
Author(s): Omodaka K(1), Kurimoto T, Nakamura O, Sato K, Yasuda M, Tanaka Y, Himori N, Yokoyama Y, Nakazawa T 1 Department of Ophthalmology and...
September 30, 2014
Optic Nerve Head Blood Flow Response to Reduced Ocular Perfusion Pressure by Alteration of Either the Blood Pressure or Intraocular Pressure
Author(s): Wang L(1), Cull GA, Fortune B. 1 Devers Eye Institute, Legacy Research Institute, Portland, OR, USA. ABSTRACT PURPOSE: To test the...
July 31, 2014
Discovery and Functional Annotation of SIX6 Variants in Primary Open-Angle Glaucoma
Author(s): Ulmer Carnes M(1), Liu YP(2), Allingham RR(3), Whigham BT(3), Havens S(3), Garrett ME(1), Qiao C(4); NEIGHBORHOOD Consortium...
June 30, 2014
MMPs in the neuroretina and optic nerve: modulators of glaucoma pathogenesis and repair?
Author(s): De Groef L(1), Van Hove I, Dekeyster E, Stalmans I, Moons L. 1 Laboratory of Neural Circuit Development and Regeneration, Animal...
May 31, 2014
γ-Synuclein Antibodies Have Neuroprotective Potential on Neuroretinal Cells via Proteins of the Mitochondrial Apoptosis Pathway
Author(s): Wilding C, Bell K, Beck S, Funke S, Pfeiffer N, Grus FH. Experimental Ophthalmology, Department of Ophthalmology, Medical Center of the...
April 30, 2014
Mitochondrial DNA Variant Discovery in Normal-Tension Glaucoma Patients by Next-Generation Sequencing
Author(s): Jeoung JW(1), Seong MW, Park SS, Kim DM, Kim SH, Park KH. 1 Department of Ophthalmology, Seoul National University Hospital, Seoul,...
March 31, 2014
Emerging novel roles of neuropeptide Y in the retina: From neuromodulation to neuroprotection
Author(s): Santos-Carvalho A (1), Alvaro AR (2), Martins J (3), Ambrósio AF (4), Cavadas C (5) Neuropeptide Y (NPY) and NPY receptors are widely...
February 28, 2014
Regulation of Plasticity and Fibrogenic Activity of Trabecular Meshwork Cells by Rho GTPase Signaling
Author(s): Pattabiraman PP, Maddala R, Rao PV. Department of Ophthalmology, Duke University School of Medicine, Durham, NC, 27710. Glaucoma, a...
January 31, 2014
Anti-Connective Tissue Growth Factor Antibody Treatment Reduces Extracellular Matrix production in Trabecular Meshwork and Lamina Cribrosa cells
Author(s): Wallace DM, Clark AF, Lipson K, Andrews D, Crean J, O'Brien CJ. PURPOSE: We have previously demonstrated elevated levels of Connective...
December 31, 2013
Identification of retinal ganglion cell neuroprotection conferred by platelet-derived growth factor through analysis of the mesenchymal stem cell secretome
Author(s): Johnson TV, Dekorver NW, Levasseur VA, Osborne A, Tassoni A, Lorber B, Heller JP, Villasmil R, Bull ND, Martin KR, Tomarev SI 1 Section...
November 30, 2013
Immune response against ocular tissues after immunization with optic nerve antigens in a model of autoimmuneglaucoma
Author(s): Joachim SC, Reinehr S, Kuehn S, Laspas P, Gramlich OW, Kuehn M, Tischoff I, von Pein HD, Dick HB, Grus FH Experimental Eye Research...
October 31, 2013
Onset and Progression of Peripapillary Retinal Nerve Fiber Layer (RNFL) Retardance Changes Occur Earlier than RNFL Thickness Changes in Experimental Glaucoma
Author(s): Fortune B, Burgoyne CF, Cull G, Reynaud J, Wang L. Devers Eye Institute, Legacy Research Institute, 1225 NE 2nd Avenue, 3rd Floor,...
September 30, 2013
Ocular Rigidity, Outflow facility, Ocular Pulse Amplitude and Pulsatile Ocular Blood Flow in Open AngleGlaucoma; a manometric study
Author(s): Dastiridou AI, Tsironi EE, Tsilimbaris M, Ginis H, Karyotakis N, Cholevas P, Androudi S, Pallikaris IG. Ophthalmology Department,...
July 31, 2013
Acetylcholinesterase inhibition promotes retinal vasoprotection and increases ocular blood flow in experimental glaucoma
Author(s): Almasieh M, Macintyre JN, Pouliot M, Casanova C, Vaucher E, Kelly ME, Di Polo A. Department of Pathology and Cell Biology and Groupe de...
June 30, 2013