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Balancing Glaucoma Care: Tackling Overdiagnosis and Overtreatment to Preserve Patient Quality of Life
The Science behind the Tip In contrast to underdiagnosis, which has been described in...
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Treatment Outcomes Comparing the Paul and Baerveldt Glaucoma Implants After One Year of Follow-Up
OBJECTIVE: To compare efficacy and safety profiles of the PGI and BGI in the treatment of...
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Evaluating Primary Treatment for People with Advanced Glaucoma: Five-Year Results of the Treatment of Advanced Glaucoma Study
Purpose: To determine whether primary trabeculectomy or medical treatment produces better...
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Activation of the ROCK/MYLK Pathway Affects Complex Molecular and Morphological Changes of the Trabecular Meshwork Associated With Ocular Hypertension
Purpose: The Rho-associated protein kinase and myosin light chain kinase (ROCK/MYLK) pathway...
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The relationship between multiple deprivation and severity of glaucoma at diagnosis
BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with...
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Angle Closure SIG
SIG Corner Editor: Hana Abouzeid Chair: John Thygesen Co-chair: Gus Gazzard The goal of this SIG...
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Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis
Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee...
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Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients
Vitreous traction can cause artifacts that may obscure RNFL thinning, potentially leading to...
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Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank
Author(s): Oana A Zeleznik ° (1,2), Jae H Kang ° (3,4), Jessica Lasky-Su (3,4), A Heather...
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Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists
Author(s): Mário Lima-Fontes (1), Ana Faria-Pereira (1), Mariana Leuzinger-Dias (1), Marta Inês...
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Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure
The mechanism is thought to be an idiosyncratic reaction to sulphonamides, similar to that which...
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Cataract Surgery in Patients with Functioning Glaucoma Filtration Surgery
The accelerated development of cataract is frequently seen in the years following glaucoma...
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Relative Contributions of Intraocular and Cerebrospinal Fluid Pressures to the Biomechanics of the Lamina Cribrosa and Laminar Neural Tissues
Author(s): Alireza Karimi (1), Reza Razaghi (1), Seyed Mohammadali Rahmati (2), Christopher A Girkin (1), J Crawford Downs (1) 1 Department of...
November 30, 2022
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Consider axial length as an important parameter for your surgical decision in childhood glaucoma patients
Primary congenital glaucoma leads to blindness if not treated adequate. Typical symptoms are epiphora, photophobia and blepharospasm. The elevated...
November 30, 2022
Long-Term Alcohol Consumption and Risk of Exfoliation Glaucoma/Glaucoma Suspect among US Health Professionals
Author(s): Akiko Hanyuda (1), Bernard A Rosner (2), Janey L Wiggs (3), Kazuno Negishi (4), Louis R Pasquale (5), Jae H Kang (6) 1 Department of...
October 31, 2022
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METTL23 mutation alters histone H3R17 methylation in normal-tension glaucoma
Author(s): Yang Pan (1), Akiko Suga (1), Itaru Kimura (2), Chojiro Kimura (3), Yuriko Minegishi (1), Mao Nakayama (1), Kazutoshi Yoshitake (1),...
October 31, 2022
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Consider evaluation of corneal endothelial cell count in pseudoexfoliation patients undergoing surgery
Corneal endothelial cell loss may lead to corneal decompensation with loss of vision, which may necessitate future endothelial transplantation for...
October 31, 2022
Classification of Visual Field Abnormalities in Highly Myopic Eyes without Pathologic Change
Author(s): Fengbin Lin (1), Shida Chen (1), Yunhe Song (1), Fei Li (1), Wei Wang (1), Zhenni Zhao (2), Xinbo Gao (1), Peiyuan Wang (1), Ling Jin...
September 30, 2022
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Single-cell transcriptome analysis of regenerating RGCs reveals potent glaucoma neural repair genes
Author(s): Liang Li (1), Fang Fang (2), Xue Feng (1), Pei Zhuang (1), Haoliang Huang (1), Pingting Liu (1), Liang Liu (1), Adam Z Xu (3), Lei S Qi...
September 30, 2022
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When glaucoma is not glaucoma
An increased excavation of the optic nerve head is usually associated to glaucoma, but other optic neuropathies may also display an increased...
September 30, 2022
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External Validation and Clinical Applicability of Two Optical Coherence Tomography-Based Risk Calculators for Detecting Glaucoma
Author(s): Néstor Ventura-Abreu (1), Marc Biarnés (2), Sofia Batlle-Ferrando (1), María Teresa Carrión-Donderis (1), Rafael Castro-Domínguez (1),...
September 30, 2022
Next Generation Partnership SIG
SIG Corner Editor: Hana Abouzeid Chair: Gauti Johannesson Co-chairs: Esther Hoffmann, Anthony Khawaja, Francesco Oddone The goal of this SIG is to...
July 31, 2022
Comparison of the Effects of Latanoprostene Bunod and Timolol on Retinal Blood Vessel Density: A Randomized Clinical Trial
Author(s): Nevin W El-Nimri (1), Sasan Moghimi (1), Rafaella C Penteado (1), Elham Ghahari (1), Diya Yang (2), Nicole Brye (1), James Proudfoot...
July 31, 2022
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Core transcription programs controlling injury-induced neurodegeneration of retinal ganglion cells
Author(s): Feng Tian (1), Yuyan Cheng (2), Songlin Zhou (1), Qianbin Wang (1), Aboozar Monavarfeshani (3), Kun Gao (2), Weiqian Jiang (1), Riki...
July 30, 2022
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Be aware of IOP elevation in children treated with systemic glucocorticoids
Children have a high risk of developing IOP elevation with topical steroid-treatment, but may also develop it after systemic treatment (1–3). The...
July 30, 2022
Screening for Glaucoma in Adults: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force
Author(s): Roger Chou (1), Shelley Selph (1,2), Ian Blazina (1), Christina Bougatsos (1), Rebecca Jungbauer (1), Rongwei Fu (1,3), Sara Grusing...
June 30, 2022
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Intelligent wireless theranostic contact lens for electrical sensing and regulation of intraocular pressure
Author(s): Cheng Yang (1), Qianni Wu (2), Junqing Liu (3), Jingshan Mo (1), Xiangling Li (1,4), Chengduan Yang (1,5), Ziqi Liu (1), Jingbo Yang...
June 30, 2022
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UGH syndrome should be considered in every pseudophakic patient, with active unilateral inflammation and elevated intraocular pressure
Uveitis-Glaucoma-Hyphaema (UGH) Syndrome is a rare syndrome characterized by iris transillumination defects, microhyphaemas and pigmentary...
June 30, 2022
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Intravenous hypertonic saline to reduce intraocular pressure: the effect of splitting the bolus
Author(s): Pia Inborr (1), Mika Harju (1), Tero T Kivelä (1) 1 Department of Ophthalmology, University of Helsinki and Helsinki University...
June 30, 2022
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Hypotony-related complications, not numerical hypotony, should alarm the clinician
Chronic hypotony, defined as a pressure of ≤5 mmHg for >3 months, may occur after glaucoma surgery (1,2). Despite being traditionally regarded...
May 31, 2022
Nicotinamide and Pyruvate for Neuroenhancement in Open-Angle Glaucoma: A Phase 2 Randomized Clinical Trial
Author(s): Carlos Gustavo De Moraes (1), Simon W M John (1,2,3), Pete A Williams (4), Dana M Blumberg (1), George A Cioffi (1), Jeffrey M Liebmann...
May 31, 2022
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Monocyte-derived SDF1 supports optic nerve regeneration and alters retinal ganglion cells' response to Pten deletion
Author(s): Lili Xie (1,2), Ling-Ping Cen (1,2 3), Yiqing Li (1,2,4), Hui-Ya Gilbert (1,2), Oleksandr Strelko (1,2), Cynthia Berlinicke (5,6,7,8),...
May 31, 2022
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When choosing a glaucoma operation, be guided by the target intra-ocular pressure (IOP)
In recent years, we have seen a vast expansion of incisional surgical techniques for glaucoma with a wide range of long-term efficacy and safety...
April 30, 2022
Is Genetic Risk for Sleep Apnea Causally Linked With Glaucoma Susceptibility?
Author(s): Nathan Ingold (1,2), Adrian I Campos (1,3), Xikun Han (1,3), Jue-Sheng Ong (1), Puya Gharahkhani (1), David A Mackey (4), Miguel E...
April 30, 2022
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Is Genetic Risk for Sleep Apnea Causally Linked With Glaucoma Susceptibility?
Author(s): Nathan Ingold (1,2), Adrian I Campos (1,3), Xikun Han (1,3), Jue-Sheng Ong (1), Puya Gharahkhani (1), David A Mackey (4), Miguel E...
April 30, 2022
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Be aware of glaucoma therapy-related ocular surface disease when planning filtration surgery!
Glaucoma eye drops, especially when containing preservatives, are responsible for clinical or subclinical ocular surface alterations (1). Amongst...
March 31, 2022
Policy-Driven, Multimodal Deep Learning for Predicting Visual Fields from the Optic Disc and Optical Coherence Tomography Imaging
Author(s): Yuka Kihara (1), Giovanni Montesano (2), Andrew Chen (1), Nishani Amerasinghe (3), Chrysostomos Dimitriou (4), Aby Jacob (3), Almira...
March 31, 2022