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F4H5 Alleviates Increased Outflow Resistance Induced by Emulsified Silicone Oil In Vitro
Purpose: The purpose of this study was to investigate the effect of emulsified silicone oil on...
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The scleral spur
The scleral spur is a ring-shaped structure, primarily collagen with 5% elastin (1), providing...
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Neuroprotection in Glaucoma: Investigational, Complementary to IOP-Lowering
Tip: Neuroprotection in glaucoma is investigational and may be considered only as an adjunct,...
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Evaluating High Intraocular Pressure Criteria for Failure in Glaucoma Surgery: Impact on Estimated Success and Visual Field Rates
Purpose: Review high intraocular pressure (IOP) thresholds used as failure criteria in glaucoma...
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Gonioscopy is always essential
Angle closure is defined by iridotrabecular contact of ≥180° (1) and the presence or development...
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Association of Blood Pressure and Retinal Nerve Fiber Layer Rates of Thinning in Patients with Moderate to Advanced Glaucoma
Objective: To investigate the influence of baseline blood pressure (BP) on retinal nerve fiber...
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Aqueous Humor Antioxidants in Glaucoma: Correlations With Subtypes, Intraocular Pressure, and Medication Use - A Prospective Study
Purpose: To investigate the correlations between aqueous humor total antioxidant capacity (TAC)...
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Care Delivery
SIG Corner Editor: Hana Abouzeid Chair: Anton B. Hommer Co-chair: Gabor Hollo Update on ongoing...
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Comparative Study of Early Safety and Effectiveness Outcomes of the PreserFlo MicroShunt with and without an Intraluminal Suture Stent
Objective: To assess the early safety and effectiveness outcomes of the PreserFlo MicroShunt with...
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Iris Crypts Could Reduce the Chance of Angle Closure: A Computational Biomechanics Study Derived From Clinical and Human Iris Data
Purpose: To investigate the effect of crypts during pupil constriction and dilation on the...
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Glaucoma drainage devices - Is the Paul glaucoma implant suitable for children with glaucoma?
Only a few studies exist on the Paul glaucoma device in children with glaucoma. Compared to Ahmed...
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Comparison of Methods to Deliver Mitomycin C in Trabeculectomy Surgery: a Systematic Review and Meta-analysis
Purpose: Compare different methods to deliver Mitomycin C (MMC) in trabeculectomy surgery....
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Factors associated with progression to primary angle closure. A post hoc analysis of the ANA-LIS trial
Objective: To evaluate baseline anterior segment risk factors associated with progression from PACS to PAC over 5 years. Design, setting,...
September 24, 2026
Adipose-derived Mesenchymal Stem Cell Exosome miR-146a-5p attenuates TGF-β2-induced transformation of human tenon's capsule fibroblasts by targeting SMAD4
Purpose: Conjunctival fibrosis is the major impediment to the success of glaucoma filtration surgery. Exosomes secreted by human adipose-derived...
September 24, 2026
Prediction of structural glaucoma progression from baseline fundus photographs using deep learning: a retrospective multicentre study
Background: Identifying patients with glaucoma who are at risk of rapid disease progression is crucial to preventing vision loss. We aimed to...
September 24, 2026
Look for the structural clues of glaucoma
Tip: Glaucoma announces itself through a few recurring structural signs: rim notching, an optic disc (papillary border) haemorrhage, an RNFL...
September 24, 2026
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Statement from Glaucoma Patients Across Europe on DICOM Adoption
As representatives of thousands of glaucoma patients across Europe and the UK, we strongly support urgent progress to improve interoperability...
July 23, 2026
Initial aqueous suppressant therapy after glaucoma drainage device implantation: a systematic review
Purpose: Aqueous suppressants (AS) are commonly used after glaucoma drainage device (GDD) surgery to limit early rises in intraocular pressure...
July 20, 2026
Conjunctival inflammation can lead to tube exposure after filtrating surgery
Tube exposure after glaucoma drainage device surgery is multifactorial; younger age is an established risk factor, while chronic ocular...
July 20, 2026
Spatial decomposition of longitudinal RNFL maps reveals distinct modes of glaucomatous progression with structure–function and genetic signatures
Purpose: To determine whether spatial decomposition of longitudinal retinal nerve fiber layer (RNFL) change maps reveals distinct modes of...
July 20, 2026
Laser trabeculoplasty
Effectiveness of laser trabeculoplasty Repeat treatment: If the first complete treatment is effective but the target pressure is not achieved or if...
July 20, 2026
Childhood glaucoma
Life-long follow-up of IOP is mandatory to avoid undetected progression. Orthoptic follow-ups as well as refractive correction are necessary to...
July 20, 2026
Retinomics as a tool for Glaucoma prediction
Purpose: To investigate retinomic changes preceding glaucoma onset and explore their predictive value. Design: A population-based, prospective...
June 24, 2026
Effects of optic nerve head structures on retinal nerve fiber layer defects in primary open angle glaucoma eyes: Analyses using retinal optical texture analysis (ROTA)
Purpose: To elucidate associations between optic nerve head (ONH) structures and the retinal nerve fiber layer optical texture analysis...
June 24, 2026
The future of glaucoma management and policy implications
Age-standardised prevalence of blindness and vision impairment [due to glaucoma] has decreased over the last 20 years in Europe. Although this is...
June 24, 2026
Bleb-forming shunts/devices without a plate
The appropriate use of antimetabolites is key to the success of bleb-forming devices (MIBS). Although higher doses of Mitomycin C result in better...
June 24, 2026
Timeless Tips to remember - Consider sources of bias when using OCT angiography
OCT angiography (OCTA) has gained great interest in glaucoma diagnosis (1, 2) and follow up(3). However, several conditions and diseases can impact...
June 24, 2026
Longitudinal visual field and quality of life change in the Treatment for Advanced Glaucoma Study
Objectives: Progressive visual field (VF) loss from glaucoma affects patients’ quality of life (QoL). While treatments aim to preserve vision, the...
June 24, 2026
Childhood glaucoma
Congenital glaucoma occurs in about 1 in 12-18,000 births among white Europeans. Incidence can be 5 to 10 times higher if consanguinity of parents...
May 21, 2026
Timeless Tips to remember - In glaucoma patients with anterior uveitis using brimonidine, one must consider `brimonidine-associated uveitis` to avoid misdiagnosis and over-treatment
Raised intraocular pressure (IOP) and secondary glaucoma due to underlying uveitis is a well-acknowledged phenomenon (1). The clinician should...
May 21, 2026
NeuProIO: A dual-action solid drug nanoparticle topical formulation for simultaneous intraocular pressure reduction and neuroprotection for glaucoma
Abstract: Glaucoma is a leading cause of irreversible blindness, primarily due to elevated intraocular pressure (IOP) that damages the retina and...
May 21, 2026
Treatment – General principles
The only proven method of preserving visual function is to reduce the intraocular pressure (IOP). EGS Guidelines, 6th Edition, Page 159 Pearls...
May 21, 2026
Long-term Persistent Angle Closure and Anatomic Changes after Laser Iridotomy in Suspected Primary Angle-Closure
Purpose: To evaluate the proportion of patients with, and anatomic predictors of, persistent angle closure 5 years after laser peripheral iridotomy...
May 21, 2026
Local toxicity of topical treatment: the role of preservatives
Therapeutic options to reduce OSD include preservative-free or BAC-free medication, decreasing the number of eye drops (e.g., by using fixed...
April 22, 2026
Laser peripheral iridotomy
Indications: Angle closure disease: high risk Primary Angle Closure Suspect, Primary Angle Closure [and] Primary Angle Closure Glaucoma; treatment...
April 22, 2026
In Vivo Comparison of Intracameral and Intravitreal Implantation of a Timolol Maleate Miniaturized Injectable Delivery System Device
Purpose: Miniaturized injectable delivery system (MIDS) devices engineered for zero-order release of timolol maleate are evaluated for intracameral...
April 20, 2026
Artificial intelligence-based glaucoma screening in primary care: a cross-sectional study and economic viability analysis of an ongoing trial
Background: Glaucoma is a leading cause of blindness and is often undiagnosed. Owing to novel artificial intelligence (AI) technology,...
April 20, 2026