• Comparative Study of Early Safety and Effectiveness Outcomes of the PreserFlo MicroShunt with and without an Intraluminal Suture Stent

    Objective: To assess the early safety and effectiveness outcomes of the PreserFlo MicroShunt with and without an intraluminal suture stent. Design:...

    Learn more...
    Comparative Study of Early Safety and Effectiveness Outcomes of the PreserFlo MicroShunt with and without an Intraluminal Suture Stent

    Comparative Study of Early Safety and Effectiveness Outcomes of the PreserFlo MicroShunt with and without an Intraluminal Suture Stent

    Objective: To assess the early safety and effectiveness outcomes of the PreserFlo MicroShunt with...

    Learn more...
  • Iris Crypts Could Reduce the Chance of Angle Closure: A Computational Biomechanics Study Derived From Clinical and Human Iris Data

    Purpose: To investigate the effect of crypts during pupil constriction and dilation on the potential for angle closure by performing finite element...

    Learn more...
    Iris Crypts Could Reduce the Chance of Angle Closure: A Computational Biomechanics Study Derived From Clinical and Human Iris Data

    Iris Crypts Could Reduce the Chance of Angle Closure: A Computational Biomechanics Study Derived From Clinical and Human Iris Data

    Purpose: To investigate the effect of crypts during pupil constriction and dilation on the...

    Learn more...
  • Glaucoma drainage devices - Is the Paul glaucoma implant suitable for children with glaucoma?

    Only a few studies exist on the Paul glaucoma device in children with glaucoma. Compared to Ahmed glaucoma Valve or Baerveldt implant, there is...

    Learn more...
    Glaucoma drainage devices - Is the Paul glaucoma implant suitable for children with glaucoma?

    Glaucoma drainage devices - Is the Paul glaucoma implant suitable for children with glaucoma?

    Only a few studies exist on the Paul glaucoma device in children with glaucoma. Compared to Ahmed...

    Learn more...
  • Comparison of Methods to Deliver Mitomycin C in Trabeculectomy Surgery: a Systematic Review and Meta-analysis

    Purpose: Compare different methods to deliver Mitomycin C (MMC) in trabeculectomy surgery. Clinical relevance: Knowing the best way to apply MMC...

    Learn more...
    Comparison of Methods to Deliver Mitomycin C in Trabeculectomy Surgery: a Systematic Review and Meta-analysis

    Comparison of Methods to Deliver Mitomycin C in Trabeculectomy Surgery: a Systematic Review and Meta-analysis

    Purpose: Compare different methods to deliver Mitomycin C (MMC) in trabeculectomy surgery....

    Learn more...
  • Aqueous Humor Antioxidants in Glaucoma: Correlations With Subtypes, Intraocular Pressure, and Medication Use - A Prospective Study

    Purpose: To investigate the correlations between aqueous humor total antioxidant capacity (TAC) and glaucoma subtypes, intraocular pressure (IOP),...

    Learn more...
    Aqueous Humor Antioxidants in Glaucoma: Correlations With Subtypes, Intraocular Pressure, and Medication Use - A Prospective Study

    Aqueous Humor Antioxidants in Glaucoma: Correlations With Subtypes, Intraocular Pressure, and Medication Use - A Prospective Study

    Purpose: To investigate the correlations between aqueous humor total antioxidant capacity (TAC)...

    Learn more...
  • Optic Disc Microvasculature Reduction and Visual Field Progression in Primary Open-Angle Glaucoma

    Purpose: To investigate the relationship between optic disc vessel density (ODVD) reduction and visual field (VF) progression in primary open-angle...

    Learn more...
    Optic Disc Microvasculature Reduction and Visual Field Progression in Primary Open-Angle Glaucoma

    Optic Disc Microvasculature Reduction and Visual Field Progression in Primary Open-Angle Glaucoma

    Purpose: To investigate the relationship between optic disc vessel density (ODVD) reduction and...

    Learn more...
  • Consider cotton wool spots as potential triggers for (non-glaucomatous) nerve fibre bundle defects

    It may be tempting to make a glaucoma diagnosis in the presence of a nerve fibre bundle defect with or without visual field defect when located in...

    Learn more...
    Consider cotton wool spots as potential triggers for (non-glaucomatous) nerve fibre bundle defects

    Consider cotton wool spots as potential triggers for (non-glaucomatous) nerve fibre bundle defects

    It may be tempting to make a glaucoma diagnosis in the presence of a nerve fibre bundle defect...

    Learn more...
  • Risk Score Predicting Primary Open-Angle Glaucoma Patients With Vascular Predisposition

    Purpose: We tested the hypothesis that a questionnaire-based risk score predicts the prevalence of patients with primary open-angle glaucoma (POAG)...

    Learn more...
    Risk Score Predicting Primary Open-Angle Glaucoma Patients With Vascular Predisposition

    Risk Score Predicting Primary Open-Angle Glaucoma Patients With Vascular Predisposition

    Purpose: We tested the hypothesis that a questionnaire-based risk score predicts the prevalence...

    Learn more...
  • Not every ring scotoma is due to glaucoma

    In advanced stages of glaucoma, patients may present with an annular scotoma, also known as ring scotoma, where the retinal sensitivity is...

    Learn more...
    Not every ring scotoma is due to glaucoma

    Not every ring scotoma is due to glaucoma

    In advanced stages of glaucoma, patients may present with an annular scotoma, also known as ring...

    Learn more...
  • Relationship between Blood Pressure and Rates of Glaucomatous Visual Field Progression

    Purpose: To examine the relationship between systemic arterial blood pressure (BP) and the rate of change in standard automated perimetry (SAP) in...

    Learn more...
    Relationship between Blood Pressure and Rates of Glaucomatous Visual Field Progression

    Relationship between Blood Pressure and Rates of Glaucomatous Visual Field Progression

    Purpose: To examine the relationship between systemic arterial blood pressure (BP) and the rate...

    Learn more...
  • Comparison of Outcomes of Deep Sclerectomy, Canaloplasty, and Viscocanaloplasty: A Multi-Centred Study

    Prcis: Deep sclerectomy (DS) and canaloplasty provide better intraocular pressure (IOP) control than viscocanalostomy. DS required less glaucoma...

    Learn more...
    Comparison of Outcomes of Deep Sclerectomy, Canaloplasty, and Viscocanaloplasty: A Multi-Centred Study

    Comparison of Outcomes of Deep Sclerectomy, Canaloplasty, and Viscocanaloplasty: A Multi-Centred Study

    Prcis: Deep sclerectomy (DS) and canaloplasty provide better intraocular pressure (IOP) control...

    Learn more...
  • Macular Oxygen Saturation in Glaucoma Using Retinal Oximetry of Visible Light Optical Coherence Tomography: A Pilot Study

    Purpose: A cross-sectional pilot study to compare macular oxygen saturation (sO2) and associated clinical measurements between normal and glaucoma...

    Learn more...
    Macular Oxygen Saturation in Glaucoma Using Retinal Oximetry of Visible Light Optical Coherence Tomography: A Pilot Study

    Macular Oxygen Saturation in Glaucoma Using Retinal Oximetry of Visible Light Optical Coherence Tomography: A Pilot Study

    Purpose: A cross-sectional pilot study to compare macular oxygen saturation (sO2) and associated...

    Learn more...
Malignant glaucoma

Pearl

Malignant glaucoma

Pearls Manager: Andrew Tatham Malignant glaucoma or aqueous misdirection is a rare type of secondary angle closure glaucoma most commonly...

October 20, 2020

Angle Closure - Relevant breakthroughs in this field

SIG Corner

Angle Closure - Relevant breakthroughs in this field

2.1 Should laser peripheral iridotomy (LPI) be performed in primary angle-closure suspect (PACS) patients? Last year we covered the EAGLE and ZAP...

October 01, 2020

Glaucoma progression: watch out the fellow, non-progressing eye

Tip of the month

Glaucoma progression: watch out the fellow, non-progressing eye

In clinical practice, the detection of visual field progression in one eye usually leads to management modifications in that eye. Less attention is...

September 30, 2020

Cardiovascular Disease may predict structural and functional progression in early glaucoma

Clinical paper of the month

Cardiovascular Disease may predict structural and functional progression in early glaucoma

Author(s): Henry Marshall (1), Sean Mullany (2), Ayub Qassim (2), Mark Hassall (2), Owen Siggs (2), Bronwyn Ridge (2), Thi Nguyen (2), Mona...

September 30, 2020

Association of Glaucoma Risk Genes with Retinal Nerve Fiber Layer in a Multi-ethnic Asian Population: The Singapore Epidemiology of Eye Diseases Study

Experimental Paper of the Month

Association of Glaucoma Risk Genes with Retinal Nerve Fiber Layer in a Multi-ethnic Asian Population: The Singapore Epidemiology of Eye Diseases Study

Author(s): Xiaoran Chai (1,2,3), Kok Yao Low (1,4), Yih Chung Tham (1), Miao Li Chee (1), Sahil Thakur (1), Liang Zhang (1), Nicholas Y Tan (1),...

September 30, 2020

Mutations in SPATA13/ASEF2 Cause Primary Angle Closure Glaucoma

NGP Paper

Mutations in SPATA13/ASEF2 Cause Primary Angle Closure Glaucoma

Author(s): Naushin H Waseem (1), Sancy Low (2,3,4), Amna Z Shah (3), Deepa Avisetti (5), Pia Ostergaard (6), Michael Simpson (7), Katarzyna A...

September 30, 2020

Optimising eye drop instillation

Pearl

Optimising eye drop instillation

Pearls Manager: Andrew Tatham When two eye drops are instilled 30 seconds apart, almost 50% of the first drug will be washed out. It is recommended...

September 30, 2020

Take care not to miss glaucomatous cupping in patients with small discs!

Tip of the month

Take care not to miss glaucomatous cupping in patients with small discs!

The Science behind the Tip The diagnosis of glaucoma can be missed in patients with small optic discs (1). In such patients, relative crowding of...

July 31, 2020

Longitudinal Macular Structure–Function Relationships in Glaucoma

Clinical paper of the month

Longitudinal Macular Structure–Function Relationships in Glaucoma

Author(s): Vahid Mohammadzadeh (1), Alessandro Rabiolo (2), Qiang Fu (3), Esteban Morales (1), Anne L Coleman (1), Simon K Law (1), Joseph Caprioli...

July 31, 2020

Efficacy for Differentiating Nonglaucomatous Versus Glaucomatous Optic Neuropathy Using Deep Learning Systems

Experimental Paper of the Month

Efficacy for Differentiating Nonglaucomatous Versus Glaucomatous Optic Neuropathy Using Deep Learning Systems

Author(s): Hee Kyung Yang (1), Young Jae Kim (2), Jae Yun Sung (1), Dong Hyun Kim (1), Kwang Gi Kim (3), Jeong-Min Hwang (4) 1 Department of...

July 31, 2020

The Collaborative Normal Tension Glaucoma Study (CNTGS)

Pearl

The Collaborative Normal Tension Glaucoma Study (CNTGS)

Pearls Manager: Andrew Tatham The CNTGS compared treatment versus no treatment in patients with normal tension glaucoma who had verified...

July 30, 2020

Ask your glaucoma patients about mobility rather than vision

Tip of the month

Ask your glaucoma patients about mobility rather than vision

The Science behind the Tip Self-reported visual disability in glaucoma which correlates with level of visual field loss includes bumping into...

June 30, 2020

Visual Field Outcomes from the Multicenter, Randomized Controlled Laser in Glaucoma and Ocular Hypertension Trial

Clinical paper of the month

Visual Field Outcomes from the Multicenter, Randomized Controlled Laser in Glaucoma and Ocular Hypertension Trial

Author(s): David M.Wright (1,2), Evgenia Konstantakopoulou (3,4,5), Giovanni Montesano (6), Neil Nathwani (3), Anurag Garg (3), David Garway-Heath...

June 30, 2020

Using Deep Learning to Automate Goldmann Applanation Tonometry Readings

Experimental Paper of the Month

Using Deep Learning to Automate Goldmann Applanation Tonometry Readings

Author(s): Ted Spaide (1), Yue Wu (1), Ryan T Yanagihara (1), Shu Feng (1), Omar Ghabra (1), Jonathan S Yi (1), Philip P Chen (1), Francy Moses...

June 30, 2020

Wound healing is one of the main determinants of long-term intraocular pressure control after filtering surgery

Pearl

Wound healing is one of the main determinants of long-term intraocular pressure control after filtering surgery

Pearls Manager: Andrew Tatham Risk factors for conjunctival scarring include young age, African ancestry, inflammatory eye disease, long-term...

June 18, 2020

Glaucoma patients on topical treatment should be routinely checked for signs of ocular surface disease even if they are asymptomatic

Tip of the month

Glaucoma patients on topical treatment should be routinely checked for signs of ocular surface disease even if they are asymptomatic

The Science behind the Tip The prevalence of ocular surface disease is significantly higher in glaucoma patients (1). While generally accepted that...

May 31, 2020

Franz Fankhauser: the father of the automated perimeter

Clinical paper of the month

Franz Fankhauser: the father of the automated perimeter

Author(s): Gloor BP Zürich, Switzerland. Franz Fankhauser is known as the father of automated perimetry and of the q-switched Nd:YAG laser knife....

May 31, 2020

Circadian Regulation of IOP Rhythm by Dual Pathways of Glucocorticoids and the Sympathetic Nervous System

Experimental Paper of the Month

Circadian Regulation of IOP Rhythm by Dual Pathways of Glucocorticoids and the Sympathetic Nervous System

Author(s): Ikegami K, Shigeyoshi Y, Masubuchi S PURPOSE: Elevated IOP can cause the development of glaucoma. The circadian rhythm of IOP depends on...

May 31, 2020

Individualized glaucoma treatment

Pearl

Individualized glaucoma treatment

Pearls Manager: Andrew Tatham Individualized glaucoma treatment aims at providing glaucoma management tailored to the individual needs of the...

May 30, 2020

Exfoliation SIG

SIG Corner

Exfoliation SIG

Chair: Gabor Hollo Co-chair: Anastasios Konstas The goal of this SIG is to increase ophthalmologists’ knowledge on XFS and XFG, and to support the...

May 24, 2020

Late in-the-bag intraocular lens dislocation several years after uncomplicated cataract surgery is relatively common in pseudoexfoliation

Tip of the month

Late in-the-bag intraocular lens dislocation several years after uncomplicated cataract surgery is relatively common in pseudoexfoliation

The Science behind the Tip In pseudoexfoliation syndrome (PSX) and pseudoexfoliative glaucoma (PSG) progressive zonular damage frequently leads to...

March 31, 2020

The Association between Medication Adherence and Visual Field Progression in the Collaborative Initial Glaucoma Treatment Study

Clinical paper of the month

The Association between Medication Adherence and Visual Field Progression in the Collaborative Initial Glaucoma Treatment Study

Author(s): Newman-Casey PA (1), Niziol LM (2), Gillespie BW (3), Janz NK (4), Lichter PR (2), Musch DC (5) 1 Department of Ophthalmology and Visual...

March 31, 2020

Association of Genetic Variants With Primary Open-Angle Glaucoma Among Individuals With African Ancestry

Experimental Paper of the Month

Association of Genetic Variants With Primary Open-Angle Glaucoma Among Individuals With African Ancestry

Author(s): Genetics of Glaucoma in People of African Descent (GGLAD) Consortium, Hauser MA (1,2,3,4), Allingham RR (2,3,4), Aung T (3,4,5,6), Van...

March 31, 2020

Care Delivery SIG

SIG Corner

Care Delivery SIG

SIG Corner Editor: João Barbosa Breda Chair: Anton B. Hommer Co-chair: Gábor Holló The goal of this SIG is to keep an updated overview of glaucoma...

March 31, 2020

Glaucoma Gel Implant Learning Curve in a Teaching Tertiary Hospital

NGP Paper

Glaucoma Gel Implant Learning Curve in a Teaching Tertiary Hospital

Author(s):* Raquel Esteves Marques (1,2), Nuno Pinto Ferreira (1,2), David Cordeiro Sousa (1,2,3), Joana Pinto (1,2), André Barata (1,2), Paula...

March 30, 2020