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  • How do you communicate numbers to your glaucoma patient?

    Shared decision making can reduce overtreatment, which places an unnecessary burden on the healthcare system and places the patient at risk of an...

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    How do you communicate numbers to your glaucoma patient?

    How do you communicate numbers to your glaucoma patient?

    Shared decision making can reduce overtreatment, which places an unnecessary burden on the...

    Learn more...
  • Validating and updating the OHTS-EGPS model predicting 5-year glaucoma risk among ocular hypertension patients using electronic records

    Objective: To validate and update the OHTS-EGPS model predicting risk of conversion from OHT to glaucoma using electronic medical records (EMR)....

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    Validating and updating the OHTS-EGPS model predicting 5-year glaucoma risk among ocular hypertension patients using electronic records

    Validating and updating the OHTS-EGPS model predicting 5-year glaucoma risk among ocular hypertension patients using electronic records

    Objective: To validate and update the OHTS-EGPS model predicting risk of conversion from OHT to...

    Learn more...
  • The Strain Response to Intraocular Pressure Increase in the Lamina Cribrosa of Control Subjects and Glaucoma Patients

    Purpose: The purpose of this study was to measure biomechanical strains in the lamina cribrosa (LC) of living human eyes undergoing intraocular...

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    The Strain Response to Intraocular Pressure Increase in the Lamina Cribrosa of Control Subjects and Glaucoma Patients

    The Strain Response to Intraocular Pressure Increase in the Lamina Cribrosa of Control Subjects and Glaucoma Patients

    Purpose: The purpose of this study was to measure biomechanical strains in the lamina cribrosa...

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  • Psychological Stress and Intraocular Pressure in Glaucoma: A Randomized Controlled Trial

    Purpose: To evaluate the intraocular pressure (IOP) behavior after applying a standardized protocol to induce psychological stress in patients with...

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    Psychological Stress and Intraocular Pressure in Glaucoma: A Randomized Controlled Trial

    Psychological Stress and Intraocular Pressure in Glaucoma: A Randomized Controlled Trial

    Purpose: To evaluate the intraocular pressure (IOP) behavior after applying a standardized...

    Learn more...
  • Fatal beauty: which cosmetics are your glaucoma patients using?

    Colorism refers to the difference in social treatment between light-skinned and dark-skinned people. This sociological concept is a result of...

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    Fatal beauty: which cosmetics are your glaucoma patients using?

    Fatal beauty: which cosmetics are your glaucoma patients using?

    Colorism refers to the difference in social treatment between light-skinned and dark-skinned...

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  • The relationship between multiple deprivation and severity of glaucoma at diagnosis

    BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with many individuals living with more than one illness....

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    The relationship between multiple deprivation and severity of glaucoma at diagnosis

    The relationship between multiple deprivation and severity of glaucoma at diagnosis

    BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with...

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  • Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

    Author(s): Oana A Zeleznik ° (1,2), Jae H Kang ° (3,4), Jessica Lasky-Su (3,4), A Heather Eliassen (3,4,5,6), Lisa Frueh (3), Clary B Clish (7),...

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    Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

    Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

    Author(s): Oana A Zeleznik ° (1,2), Jae H Kang ° (3,4), Jessica Lasky-Su (3,4), A Heather...

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  • Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Vitreous traction can cause artifacts that may obscure RNFL thinning, potentially leading to misinterpretation of disease progression. Studies have...

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    Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Vitreous traction can cause artifacts that may obscure RNFL thinning, potentially leading to...

    Learn more...
  • Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee (4), Sung Ryul Shim (5), Ahnul Ha (6) 1 Department...

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    Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee...

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  • Angle Closure SIG

    SIG Corner Editor: Hana Abouzeid Chair: John Thygesen Co-chair: Gus Gazzard The goal of this SIG is to further the promotion of knowledge about the...

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    Angle Closure SIG

    Angle Closure SIG

    SIG Corner Editor: Hana Abouzeid Chair: John Thygesen Co-chair: Gus Gazzard The goal of this SIG...

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  • Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists

    Author(s): Mário Lima-Fontes (1), Ana Faria-Pereira (1), Mariana Leuzinger-Dias (1), Marta Inês Silva (1), João Barbosa-Breda (1,2,3), Joana Araújo...

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    Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists

    Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists

    Author(s): Mário Lima-Fontes (1), Ana Faria-Pereira (1), Mariana Leuzinger-Dias (1), Marta Inês...

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  • Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure

    The mechanism is thought to be an idiosyncratic reaction to sulphonamides, similar to that which can occur with drugs such as topiramate. The...

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    Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure

    Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure

    The mechanism is thought to be an idiosyncratic reaction to sulphonamides, similar to that which...

    Learn more...
Psychological Stress and Intraocular Pressure in Glaucoma: A Randomized Controlled Trial

Clinical paper of the month

Psychological Stress and Intraocular Pressure in Glaucoma: A Randomized Controlled Trial

Purpose: To evaluate the intraocular pressure (IOP) behavior after applying a standardized protocol to induce psychological stress in patients with...

December 09, 2024

Quality of Life and Primary Open-Angle Glaucoma in the Ocular Hypertension Treatment Study

Clinical paper of the month

Quality of Life and Primary Open-Angle Glaucoma in the Ocular Hypertension Treatment Study

Key Points Question: Do participants in the Ocular Hypertension Treatment Study with preperimetric primary open-angle glaucoma (POAG) have lower...

November 12, 2024

Relationship between Intraocular Pressure Fluctuation and Visual Field Progression Rates in the United Kingdom Glaucoma Treatment Study

Clinical paper of the month

Relationship between Intraocular Pressure Fluctuation and Visual Field Progression Rates in the United Kingdom Glaucoma Treatment Study

Purpose: To investigate whether intraocular pressure (IOP) fluctuation is associated independently with the rate of visual field (VF) progression...

October 15, 2024

Evaluating Primary Treatment for People with Advanced Glaucoma: Five-Year Results of the Treatment of Advanced Glaucoma Study

Clinical paper of the month

Evaluating Primary Treatment for People with Advanced Glaucoma: Five-Year Results of the Treatment of Advanced Glaucoma Study

Purpose: To determine whether primary trabeculectomy or medical treatment produces better outcomes in terms of quality of life (QoL), clinical...

September 12, 2024

Peripheral blood mononuclear cell respiratory function is associated with progressive glaucomatous vision loss

Clinical paper of the month

Peripheral blood mononuclear cell respiratory function is associated with progressive glaucomatous vision loss

Intraocular pressure (IOP) is currently the only modifiable risk factor for glaucoma and all licensed treatments lower IOP. However, many patients...

July 11, 2024

Short-term Detection of Fast Progressors in Glaucoma: The Fast Progression Assessment through Clustered Evaluation (Fast-PACE) Study

Clinical paper of the month

Short-term Detection of Fast Progressors in Glaucoma: The Fast Progression Assessment through Clustered Evaluation (Fast-PACE) Study

Purpose: To evaluate the performance of an intensive, clustered testing approach in identifying eyes with rapid glaucoma progression over 6 months...

June 16, 2024

Racial Differences in Diagnostic Accuracy of Retinal Nerve Fiber Layer Thickness in Primary Open-Angle Glaucoma

Clinical paper of the month

Racial Differences in Diagnostic Accuracy of Retinal Nerve Fiber Layer Thickness in Primary Open-Angle Glaucoma

Purpose: To evaluate the diagnostic accuracy of retinal nerve fiber layer thickness (RNFLT) by spectral-domain optical coherence tomography (OCT)...

May 15, 2024

Comparison of intraocular pressure profiles during the water drinking test and the modified diurnal tension curve

Clinical paper of the month

Comparison of intraocular pressure profiles during the water drinking test and the modified diurnal tension curve

Objectives: To compare intraocular pressure (IOP) during the water drinking test (WDT) and modified diurnal tension curve (mDTC) in open-angle...

April 15, 2024

Cost-effectiveness of primary surgical versus primary medical management in the treatment of patients presenting with advanced glaucoma

Clinical paper of the month

Cost-effectiveness of primary surgical versus primary medical management in the treatment of patients presenting with advanced glaucoma

Synopsis: Advanced glaucoma is associated with sight loss. This within-trial economic evaluation compares medical and surgical management...

March 14, 2024

Retinal Nerve Fiber Layer Optical Texture Analysis

Clinical paper of the month

Retinal Nerve Fiber Layer Optical Texture Analysis

PURPOSE: To apply retinal nerve fiber layer (RNFL) optical texture analysis (ROTA) to investigate the prevalence, patterns, and risk factors of...

February 12, 2024

A multi-cohort genome-wide association study in African ancestry individuals reveals risk loci for primary open-angle glaucoma.

Clinical paper of the month

A multi-cohort genome-wide association study in African ancestry individuals reveals risk loci for primary open-angle glaucoma.

PURPOSE: Glaucoma represents a pressing public health need among African ancestry individuals. This study provides novel insight into the genetic...

January 15, 2024

Validating Trend-Based End Points for Neuroprotection Trials in Glaucoma

Clinical paper of the month

Validating Trend-Based End Points for Neuroprotection Trials in Glaucoma

PURPOSE: The purpose of this study was to evaluate the power of trend-based visual field (VF) progression end points against long-term development...

December 17, 2023

European Glaucoma Society research priorities for glaucoma care

Clinical paper of the month

European Glaucoma Society research priorities for glaucoma care

Background/Aims: The goal of health research is to improve patients care and outcomes. Thus, it is essential that research addresses questions that...

November 15, 2023

MERCURY‑3: a randomized comparison of netarsudil/latanoprost and bimatoprost/timolol in open‑angle glaucoma and ocular hypertension

Clinical paper of the month

MERCURY‑3: a randomized comparison of netarsudil/latanoprost and bimatoprost/timolol in open‑angle glaucoma and ocular hypertension

Author(s): Ingeborg Stalmans1,2 · Kin Sheng Lim3 · Francesco Oddone4 · Marek Fichtl5,6 · Jose I. Belda7,8 · Anton Hommer9 · Guna Laganovska10 ·...

October 15, 2023

Intravitreal bevacizumab improves trabeculectomy survival at 12 months: the bevacizumab in trabeculectomy study-a randomised clinical trial

Clinical paper of the month

Intravitreal bevacizumab improves trabeculectomy survival at 12 months: the bevacizumab in trabeculectomy study-a randomised clinical trial

Author(s): John A Landers, Sean Mullany, Jamie E Craig 1 Ophthalmology, Flinders University of South Australia, Adelaide, South Australia,...

September 15, 2023

Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

Clinical paper of the month

Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee (4), Sung Ryul Shim (5), Ahnul Ha (6) 1 Department...

July 30, 2023

Fast Progressors in Glaucoma: Prevalence Based on Global and Central Visual Field Loss

Clinical paper of the month

Fast Progressors in Glaucoma: Prevalence Based on Global and Central Visual Field Loss

Author(s): Aidan B Jackson (1), Keith R Martin (2), Michael A Coote (1), Felipe A Medeiros (3), Christopher A Girkin (4), Massimo A Fazio (4),...

June 30, 2023

Validation of Rates of Mean Deviation Change as Clinically Relevant End Points for Glaucoma Progression

Clinical paper of the month

Validation of Rates of Mean Deviation Change as Clinically Relevant End Points for Glaucoma Progression

Author(s): Felipe A Medeiros (1), Alessandro A Jammal (2) 1 Vision, Imaging and Performance Laboratory, Duke Eye Center, Duke University, Durham,...

May 31, 2023

MIND diet lowers risk of open-angle glaucoma: the Rotterdam Study

Clinical paper of the month

MIND diet lowers risk of open-angle glaucoma: the Rotterdam Study

Author(s): Joëlle E Vergroesen (1,2), Tosca O E de Crom (2), Cornelia M van Duijn (3), Trudy Voortman (2,4), Caroline C W Klaver (1,2,5,6), Wishal...

April 30, 2023

Evidence-Based Guidelines for the Number of Peripapillary OCT Scans Needed to Detect Glaucoma Worsening

Clinical paper of the month

Evidence-Based Guidelines for the Number of Peripapillary OCT Scans Needed to Detect Glaucoma Worsening

Author(s): Chris Bradley (1), Kaihua Hou (2), Patrick Herbert (2), Mathias Unberath (2), Michael V Boland (3), Pradeep Ramulu (4), Jithin Yohannan...

March 01, 2023

Manhattan Vision Screening and Follow-up Study (NYC-SIGHT): Baseline Results and Costs of a Cluster-Randomized Trial

Clinical paper of the month

Manhattan Vision Screening and Follow-up Study (NYC-SIGHT): Baseline Results and Costs of a Cluster-Randomized Trial

Author(s): Lisa A Hark (1), Jason D Horowitz (2), Prakash Gorroochurn (3), Lisa Park (2), Qing Wang (2), Daniel F Diamond (2), Noga Harizman (2),...

February 28, 2023

Laser in Glaucoma and Ocular Hypertension (LiGHT) Trial: Six-Year Results of Primary Selective Laser Trabeculoplasty versus Eye Drops for the Treatment of Glaucoma and Ocular Hypertension

Clinical paper of the month

Laser in Glaucoma and Ocular Hypertension (LiGHT) Trial: Six-Year Results of Primary Selective Laser Trabeculoplasty versus Eye Drops for the Treatment of Glaucoma and Ocular Hypertension

Author(s): Gus Gazzard (1), Evgenia Konstantakopoulou (2), David Garway-Heath (3), Mariam Adeleke (4), Victoria Vickerstaff (5), Gareth Ambler (6),...

January 31, 2023

Estimating the Length of the Preclinical Detectable Phase for Open-Angle Glaucoma

Clinical paper of the month

Estimating the Length of the Preclinical Detectable Phase for Open-Angle Glaucoma

Author(s): Johan Aspberg (1,2), Anders Heijl (1,2), Boel Bengtsson (1) 1 Department of Clinical Sciences in Malmö, Ophthalmology, Lund University,...

December 29, 2022

Association of High Polygenic Risk With Visual Field Worsening Despite Treatment in Early Primary Open-Angle Glaucoma

Clinical paper of the month

Association of High Polygenic Risk With Visual Field Worsening Despite Treatment in Early Primary Open-Angle Glaucoma

Author(s): Owen M Siggs (1,2), Ayub Qassim (1), Xikun Han (3), Henry N Marshall (1), Sean Mullany (1), Weixiong He (3), Emmanuelle Souzeau (1),...

November 30, 2022

Long-Term Alcohol Consumption and Risk of Exfoliation Glaucoma/Glaucoma Suspect among US Health Professionals

Clinical paper of the month

Long-Term Alcohol Consumption and Risk of Exfoliation Glaucoma/Glaucoma Suspect among US Health Professionals

Author(s): Akiko Hanyuda (1), Bernard A Rosner (2), Janey L Wiggs (3), Kazuno Negishi (4), Louis R Pasquale (5), Jae H Kang (6) 1 Department of...

October 31, 2022