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Identification of Optic Nerve–Related Biomarkers in Primary Open-Angle Glaucoma Based on Comprehensive Bioinformatics and Mendelian Randomization
Purpose: Glaucoma is the primary cause of permanent vision loss worldwide. However, the...
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Quality of Life and Primary Open-Angle Glaucoma in the Ocular Hypertension Treatment Study
Importance: If preperimetric glaucoma reduces patient-reported vision-related quality of life...
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Fatal beauty: which cosmetics are your glaucoma patients using?
Colorism refers to the difference in social treatment between light-skinned and dark-skinned...
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The relationship between multiple deprivation and severity of glaucoma at diagnosis
BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with...
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Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank
Author(s): Oana A Zeleznik ° (1,2), Jae H Kang ° (3,4), Jessica Lasky-Su (3,4), A Heather...
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Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients
Vitreous traction can cause artifacts that may obscure RNFL thinning, potentially leading to...
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Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis
Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee...
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Angle Closure SIG
SIG Corner Editor: Hana Abouzeid Chair: John Thygesen Co-chair: Gus Gazzard The goal of this SIG...
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Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists
Author(s): Mário Lima-Fontes (1), Ana Faria-Pereira (1), Mariana Leuzinger-Dias (1), Marta Inês...
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Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure
The mechanism is thought to be an idiosyncratic reaction to sulphonamides, similar to that which...
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Cataract Surgery in Patients with Functioning Glaucoma Filtration Surgery
The accelerated development of cataract is frequently seen in the years following glaucoma...
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Quality of Life and Primary Open-Angle Glaucoma in the Ocular Hypertension Treatment Study
Importance: If preperimetric glaucoma reduces patient-reported vision-related quality of life (VRQoL), clinicians might consider earlier and more...
November 12, 2024
Relationship between Intraocular Pressure Fluctuation and Visual Field Progression Rates in the United Kingdom Glaucoma Treatment Study
Purpose: To investigate whether intraocular pressure (IOP) fluctuation is associated independently with the rate of visual field (VF) progression...
October 15, 2024
Evaluating Primary Treatment for People with Advanced Glaucoma: Five-Year Results of the Treatment of Advanced Glaucoma Study
Purpose: To determine whether primary trabeculectomy or medical treatment produces better outcomes in terms of quality of life (QoL), clinical...
September 12, 2024
Peripheral blood mononuclear cell respiratory function is associated with progressive glaucomatous vision loss
Intraocular pressure (IOP) is currently the only modifiable risk factor for glaucoma and all licensed treatments lower IOP. However, many patients...
July 11, 2024
Short-term Detection of Fast Progressors in Glaucoma: The Fast Progression Assessment through Clustered Evaluation (Fast-PACE) Study
Purpose: To evaluate the performance of an intensive, clustered testing approach in identifying eyes with rapid glaucoma progression over 6 months...
June 16, 2024
Racial Differences in Diagnostic Accuracy of Retinal Nerve Fiber Layer Thickness in Primary Open-Angle Glaucoma
Purpose: To evaluate the diagnostic accuracy of retinal nerve fiber layer thickness (RNFLT) by spectral-domain optical coherence tomography (OCT)...
May 15, 2024
Comparison of intraocular pressure profiles during the water drinking test and the modified diurnal tension curve
Objectives: To compare intraocular pressure (IOP) during the water drinking test (WDT) and modified diurnal tension curve (mDTC) in open-angle...
April 15, 2024
Cost-effectiveness of primary surgical versus primary medical management in the treatment of patients presenting with advanced glaucoma
Synopsis: Advanced glaucoma is associated with sight loss. This within-trial economic evaluation compares medical and surgical management...
March 14, 2024
Retinal Nerve Fiber Layer Optical Texture Analysis
PURPOSE: To apply retinal nerve fiber layer (RNFL) optical texture analysis (ROTA) to investigate the prevalence, patterns, and risk factors of...
February 12, 2024
A multi-cohort genome-wide association study in African ancestry individuals reveals risk loci for primary open-angle glaucoma.
PURPOSE: Glaucoma represents a pressing public health need among African ancestry individuals. This study provides novel insight into the genetic...
January 15, 2024
Validating Trend-Based End Points for Neuroprotection Trials in Glaucoma
PURPOSE: The purpose of this study was to evaluate the power of trend-based visual field (VF) progression end points against long-term development...
December 17, 2023
European Glaucoma Society research priorities for glaucoma care
Background/Aims: The goal of health research is to improve patients care and outcomes. Thus, it is essential that research addresses questions that...
November 15, 2023
MERCURY‑3: a randomized comparison of netarsudil/latanoprost and bimatoprost/timolol in open‑angle glaucoma and ocular hypertension
Author(s): Ingeborg Stalmans1,2 · Kin Sheng Lim3 · Francesco Oddone4 · Marek Fichtl5,6 · Jose I. Belda7,8 · Anton Hommer9 · Guna Laganovska10 ·...
October 15, 2023
Intravitreal bevacizumab improves trabeculectomy survival at 12 months: the bevacizumab in trabeculectomy study-a randomised clinical trial
Author(s): John A Landers, Sean Mullany, Jamie E Craig 1 Ophthalmology, Flinders University of South Australia, Adelaide, South Australia,...
September 15, 2023
Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis
Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee (4), Sung Ryul Shim (5), Ahnul Ha (6) 1 Department...
July 30, 2023
Fast Progressors in Glaucoma: Prevalence Based on Global and Central Visual Field Loss
Author(s): Aidan B Jackson (1), Keith R Martin (2), Michael A Coote (1), Felipe A Medeiros (3), Christopher A Girkin (4), Massimo A Fazio (4),...
June 30, 2023
Validation of Rates of Mean Deviation Change as Clinically Relevant End Points for Glaucoma Progression
Author(s): Felipe A Medeiros (1), Alessandro A Jammal (2) 1 Vision, Imaging and Performance Laboratory, Duke Eye Center, Duke University, Durham,...
May 31, 2023
MIND diet lowers risk of open-angle glaucoma: the Rotterdam Study
Author(s): Joëlle E Vergroesen (1,2), Tosca O E de Crom (2), Cornelia M van Duijn (3), Trudy Voortman (2,4), Caroline C W Klaver (1,2,5,6), Wishal...
April 30, 2023
Evidence-Based Guidelines for the Number of Peripapillary OCT Scans Needed to Detect Glaucoma Worsening
Author(s): Chris Bradley (1), Kaihua Hou (2), Patrick Herbert (2), Mathias Unberath (2), Michael V Boland (3), Pradeep Ramulu (4), Jithin Yohannan...
March 01, 2023
Manhattan Vision Screening and Follow-up Study (NYC-SIGHT): Baseline Results and Costs of a Cluster-Randomized Trial
Author(s): Lisa A Hark (1), Jason D Horowitz (2), Prakash Gorroochurn (3), Lisa Park (2), Qing Wang (2), Daniel F Diamond (2), Noga Harizman (2),...
February 28, 2023
Laser in Glaucoma and Ocular Hypertension (LiGHT) Trial: Six-Year Results of Primary Selective Laser Trabeculoplasty versus Eye Drops for the Treatment of Glaucoma and Ocular Hypertension
Author(s): Gus Gazzard (1), Evgenia Konstantakopoulou (2), David Garway-Heath (3), Mariam Adeleke (4), Victoria Vickerstaff (5), Gareth Ambler (6),...
January 31, 2023
Estimating the Length of the Preclinical Detectable Phase for Open-Angle Glaucoma
Author(s): Johan Aspberg (1,2), Anders Heijl (1,2), Boel Bengtsson (1) 1 Department of Clinical Sciences in Malmö, Ophthalmology, Lund University,...
December 29, 2022
Association of High Polygenic Risk With Visual Field Worsening Despite Treatment in Early Primary Open-Angle Glaucoma
Author(s): Owen M Siggs (1,2), Ayub Qassim (1), Xikun Han (3), Henry N Marshall (1), Sean Mullany (1), Weixiong He (3), Emmanuelle Souzeau (1),...
November 30, 2022
Long-Term Alcohol Consumption and Risk of Exfoliation Glaucoma/Glaucoma Suspect among US Health Professionals
Author(s): Akiko Hanyuda (1), Bernard A Rosner (2), Janey L Wiggs (3), Kazuno Negishi (4), Louis R Pasquale (5), Jae H Kang (6) 1 Department of...
October 31, 2022
Classification of Visual Field Abnormalities in Highly Myopic Eyes without Pathologic Change
Author(s): Fengbin Lin (1), Shida Chen (1), Yunhe Song (1), Fei Li (1), Wei Wang (1), Zhenni Zhao (2), Xinbo Gao (1), Peiyuan Wang (1), Ling Jin...
September 30, 2022