The appropriate use of antimetabolites is key to the success of bleb-forming devices (MIBS). Although higher doses of Mitomycin C result in better IOP-lowering outcomes, they need to be balanced with the potential risks associated with stronger antimetabolite use (e.g., bleb leaks or hypotony).
EGS Guidelines, 6th Edition, Page 201
Pearls Manager: Nestor Ventura-Abreu