• Not every ring scotoma is due to glaucoma

    In advanced stages of glaucoma, patients may present with an annular scotoma, also known as ring scotoma, where the retinal sensitivity is...

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    Not every ring scotoma is due to glaucoma

    Not every ring scotoma is due to glaucoma

    In advanced stages of glaucoma, patients may present with an annular scotoma, also known as ring...

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  • Relationship between Blood Pressure and Rates of Glaucomatous Visual Field Progression

    Purpose: To examine the relationship between systemic arterial blood pressure (BP) and the rate of change in standard automated perimetry (SAP) in...

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    Relationship between Blood Pressure and Rates of Glaucomatous Visual Field Progression

    Relationship between Blood Pressure and Rates of Glaucomatous Visual Field Progression

    Purpose: To examine the relationship between systemic arterial blood pressure (BP) and the rate...

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  • Comparison of Outcomes of Deep Sclerectomy, Canaloplasty, and Viscocanaloplasty: A Multi-Centred Study

    Prcis: Deep sclerectomy (DS) and canaloplasty provide better intraocular pressure (IOP) control than viscocanalostomy. DS required less glaucoma...

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    Comparison of Outcomes of Deep Sclerectomy, Canaloplasty, and Viscocanaloplasty: A Multi-Centred Study

    Comparison of Outcomes of Deep Sclerectomy, Canaloplasty, and Viscocanaloplasty: A Multi-Centred Study

    Prcis: Deep sclerectomy (DS) and canaloplasty provide better intraocular pressure (IOP) control...

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  • Macular Oxygen Saturation in Glaucoma Using Retinal Oximetry of Visible Light Optical Coherence Tomography: A Pilot Study

    Purpose: A cross-sectional pilot study to compare macular oxygen saturation (sO2) and associated clinical measurements between normal and glaucoma...

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    Macular Oxygen Saturation in Glaucoma Using Retinal Oximetry of Visible Light Optical Coherence Tomography: A Pilot Study

    Macular Oxygen Saturation in Glaucoma Using Retinal Oximetry of Visible Light Optical Coherence Tomography: A Pilot Study

    Purpose: A cross-sectional pilot study to compare macular oxygen saturation (sO2) and associated...

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  • Childhood Glaucoma

    SIG Corner Editor: Hana Abouzeid Chair: Esther Hoffmann Co-chair: Zeynep Aktas Childhood glaucoma is a rare but severe ocular condition that can...

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    Childhood Glaucoma

    Childhood Glaucoma

    SIG Corner Editor: Hana Abouzeid Chair: Esther Hoffmann Co-chair: Zeynep Aktas Childhood glaucoma...

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  • Avoid premature removal of the intraluminal suture in glaucoma drainage devices to minimize the risk of hypotony

    While prolene suture removal is an effective method for reducing IOP at the slit-lamp, removing it too early can lead to postoperative hypotony and...

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    Avoid premature removal of the intraluminal suture in glaucoma drainage devices to minimize the risk of hypotony

    Avoid premature removal of the intraluminal suture in glaucoma drainage devices to minimize the risk of hypotony

    While prolene suture removal is an effective method for reducing IOP at the slit-lamp, removing...

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  • Biomechanics-Function in Glaucoma: Improved Visual Field Predictions from IOP-Induced Neural Strains

    Purpose: (1) To assess whether neural tissue structure and biomechanics could predict functional loss in glaucoma; (2) To evaluate the importance...

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    Biomechanics-Function in Glaucoma: Improved Visual Field Predictions from IOP-Induced Neural Strains

    Biomechanics-Function in Glaucoma: Improved Visual Field Predictions from IOP-Induced Neural Strains

    Purpose: (1) To assess whether neural tissue structure and biomechanics could predict functional...

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  • Validation of a Visual Field Prediction Tool for Glaucoma: A Multicenter Study Involving Patients With Glaucoma in the United Kingdom

    Purpose: A previously developed machine-learning approach with Kalman filtering technology accurately predicted the disease trajectory for patients...

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    Validation of a Visual Field Prediction Tool for Glaucoma: A Multicenter Study Involving Patients With Glaucoma in the United Kingdom

    Validation of a Visual Field Prediction Tool for Glaucoma: A Multicenter Study Involving Patients With Glaucoma in the United Kingdom

    Purpose: A previously developed machine-learning approach with Kalman filtering technology...

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  • Fatal beauty: which cosmetics are your glaucoma patients using?

    Colorism refers to the difference in social treatment between light-skinned and dark-skinned people. This sociological concept is a result of...

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    Fatal beauty: which cosmetics are your glaucoma patients using?

    Fatal beauty: which cosmetics are your glaucoma patients using?

    Colorism refers to the difference in social treatment between light-skinned and dark-skinned...

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  • The relationship between multiple deprivation and severity of glaucoma at diagnosis

    BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with many individuals living with more than one illness....

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    The relationship between multiple deprivation and severity of glaucoma at diagnosis

    The relationship between multiple deprivation and severity of glaucoma at diagnosis

    BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with...

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  • Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Vitreous traction can cause artifacts that may obscure RNFL thinning, potentially leading to misinterpretation of disease progression. Studies have...

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    Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Vitreous traction can cause artifacts that may obscure RNFL thinning, potentially leading to...

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  • Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee (4), Sung Ryul Shim (5), Ahnul Ha (6) 1 Department...

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    Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee...

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Early Gene Expression Changes in the Retinal Ganglion Cell Layer of a Rat Glaucoma Model

Experimental Paper of the Month

Early Gene Expression Changes in the Retinal Ganglion Cell Layer of a Rat Glaucoma Model

Author(s): Guo Y, Johnson EC, Cepurna WO, Dyck J, Doser T, Morrison JC. Ophthalmology, Oregon Health & Sciences University, Portland, United...

April 30, 2011

The most effective treatment of glaucoma associated with epithelial downgrowth is to insert a drainage implant

Tip of the month

The most effective treatment of glaucoma associated with epithelial downgrowth is to insert a drainage implant

The Science behind the Tip Epithelial downgrowth into the anterior chamber is an extremely rare cause of glaucoma after anterior segment incisional...

March 31, 2011

Investigation of the Association between Helicobacter pylori Infection and Normal Tension Glaucoma

Clinical paper of the month

Investigation of the Association between Helicobacter pylori Infection and Normal Tension Glaucoma

Author(s): Kim JM, Kim SH, Park KH, Han SY, Shim HS. Department of Ophthalmology, Sungkyunkwan University School of Medicine, Kangbuk Samsung...

March 31, 2011

Imaging the aqueous humor outflow pathway in human eyes by three-dimensional micro-computed tomography (3D micro-CT)

Experimental Paper of the Month

Imaging the aqueous humor outflow pathway in human eyes by three-dimensional micro-computed tomography (3D micro-CT)

Author(s): Hann CR, Bentley MD, Vercnocke A, Ritman EL, Fautsch MP Department of Ophthalmology, Mayo Clinic, 200 First Street SW, Rochester, MN...

March 31, 2011

Chronic miotics can be helpful in case of plateau iris configuration

Tip of the month

Chronic miotics can be helpful in case of plateau iris configuration

The Science behind the Tip Long term miotics are seldom prescribed nowadays. Still the drugs remain useful in case of plateau iris configuration, a...

February 28, 2011

Laminar and prelaminar tissue displacement during intraocular pressure elevation in glaucoma patients and healthy controls

Clinical paper of the month

Laminar and prelaminar tissue displacement during intraocular pressure elevation in glaucoma patients and healthy controls

Author(s): Agoumi Y, Sharpe GP, Hutchison DM, Nicolela MT, Artes PH, Chauhan BC. Department of Ophthalmology and Visual Sciences, Dalhousie...

February 28, 2011

Evidence for a role of angiopoietin-like 7 (ANGPTL7) in extracellular matrix formation of the human trabecular meshwork: implications for glaucoma

Experimental Paper of the Month

Evidence for a role of angiopoietin-like 7 (ANGPTL7) in extracellular matrix formation of the human trabecular meshwork: implications for glaucoma

Author(s): Comes N, Buie LK, Borrás T. Department of Ophthalmology, University of North Carolina School of Medicine, Chapel Hill, NC, USA. The...

February 28, 2011

To reduce the risk of late bleb-related infection, avoid multiple-dose eye drops in patients who have previously undergone trabeculectomy with mitomycin C

Tip of the month

To reduce the risk of late bleb-related infection, avoid multiple-dose eye drops in patients who have previously undergone trabeculectomy with mitomycin C

The Science behind the Tip Bleb-related infection is a devastating and potentially blinding late consequence of trabeculectomy, particularly if...

January 31, 2011

Intravitreal injections of neurotrophic factors secreting mesenchymal stem cells are neuroprotective in rat eyes following optic nerve transection

Clinical paper of the month

Intravitreal injections of neurotrophic factors secreting mesenchymal stem cells are neuroprotective in rat eyes following optic nerve transection

Author(s): Levkovitch-Verbin H, Sadan O, Vander S, Rosner M, Barhum Y, Melamed E, Offen D, Melamed S. Goldschleger Eye Institute, Sheba Medical...

January 31, 2011

Reversal of retinal ganglion cell dysfunction after surgical reduction of intraocular pressure

Experimental Paper of the Month

Reversal of retinal ganglion cell dysfunction after surgical reduction of intraocular pressure

Author(s): Sehi M, Grewal DS, Goodkin ML, Greenfield DS. Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami Miller...

January 31, 2011

Small field depressions can be more worrying than large ones

Tip of the month

Small field depressions can be more worrying than large ones

The Science behind the Tip Much of the decision making in modern glaucoma practice is based on automated visual field test results. Careful...

December 31, 2010

Predicting visual function from the measurements of retinal nerve fiber layer structure

Clinical paper of the month

Predicting visual function from the measurements of retinal nerve fiber layer structure

Author(s): Zhu H, Crabb DP, Schlottmann PG, Lemij HG, Reus NJ, Healey PR, Mitchell P, Ho T, Garway-Heath DF Department of Optometry and Visual...

December 31, 2010

Canadian Glaucoma Study: 3. Impact of risk factors and intraocular pressure reduction on the rates of visual field change

Clinical paper of the month

Canadian Glaucoma Study: 3. Impact of risk factors and intraocular pressure reduction on the rates of visual field change

Author(s): Chauhan BC, Mikelberg FS, Artes PH, Balazsi AG, LeBlanc RP, Lesk MR, Nicolela MT, Trope GE; Canadian Glaucoma Study Group Collaborators...

November 30, 2010

Qualitative and quantitative morphologic changes in the vasculature and extracellular matrix of the prelaminar optic nerve head in eyes with POAG

Experimental Paper of the Month

Qualitative and quantitative morphologic changes in the vasculature and extracellular matrix of the prelaminar optic nerve head in eyes with POAG

Author(s): Tektas OY, Lütjen-Drecoll E, Scholz M Institute of Anatomy II, University of Erlangen-Nuremberg, Erlangen, Germany....

November 30, 2010

The cataract surgeon should be informed that the patient has pseudo-exfoliation syndrome

Tip of the month

The cataract surgeon should be informed that the patient has pseudo-exfoliation syndrome

The Science behind the Tip Although the diagnosis of pseudo-exfoliation syndrome (PEX) with a fully dilated pupil in an elderly patient should pose...

October 31, 2010

Incidence of glaucomatous visual field loss: a ten-year follow-up from the Rotterdam Study

Clinical paper of the month

Incidence of glaucomatous visual field loss: a ten-year follow-up from the Rotterdam Study

Author(s): Czudowska MA, Ramdas WD, Wolfs RC, Hofman A, De Jong PT, Vingerling JR, Jansonius NM Department of Epidemiology, Erasmus Medical Center,...

October 31, 2010

Functional MRI signal changes in primary visual cortex corresponding to the central normal visual field of patients with primary open-angle glaucoma

Experimental Paper of the Month

Functional MRI signal changes in primary visual cortex corresponding to the central normal visual field of patients with primary open-angle glaucoma

Author(s): Qing G, Zhang S, Wang B, Wang N Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology...

October 31, 2010

If conservative measures are unsuccessful in the management of malignant glaucoma, phaco with IOL combined with posterior capsulotomy and anterior vitrectomy usually is

Tip of the month

If conservative measures are unsuccessful in the management of malignant glaucoma, phaco with IOL combined with posterior capsulotomy and anterior vitrectomy usually is

The Science behind the Tip Malignant glaucoma in a phakic eye typically follows incisional surgery for primary angle-closure glaucoma. Shallowing...

September 30, 2010

Anthropometric measures and their relation to incident primary open-angle glaucoma

Clinical paper of the month

Anthropometric measures and their relation to incident primary open-angle glaucoma

Author(s): Pasquale LR, Willett WC, Rosner BA, Kang JH Department of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear Infirmary,...

September 30, 2010

Current approaches and future prospects for stem cell rescue and regeneration of the retina and optic nerve

Experimental Paper of the Month

Current approaches and future prospects for stem cell rescue and regeneration of the retina and optic nerve

Author(s): Dahlmann-Noor A, Vijay S, Jayaram H, Limb A, Khaw PT. The 3 most common causes of visual impairment and legal blindness in developed...

September 30, 2010

Effect of sleeping in a head-up position on intraocular pressure in patients with glaucoma

Clinical paper of the month

Effect of sleeping in a head-up position on intraocular pressure in patients with glaucoma

Author(s): Buys YM, Alasbali T, Jin YP, Smith M, Gouws P, Geffen N, Flanagan JG, Shapiro CM, Trope GE Department of Ophthalmology and Vision...

August 31, 2010

Genome-wide association study of normal tension glaucoma: common variants in SRBD1 and ELOVL5 contribute to disease susceptibility

Experimental Paper of the Month

Genome-wide association study of normal tension glaucoma: common variants in SRBD1 and ELOVL5 contribute to disease susceptibility

Author(s): Writing Committee fot the Normal Tension Glaucoma Genetic Study Group of Japan Glaucoma Society, Meguro A, Inoko H, Ota M, Mizuki N,...

August 31, 2010

Clinical classification of childhood glaucomas

Clinical paper of the month

Clinical classification of childhood glaucomas

Author(s): Yeung HH, Walton DS Department of Pediatrics, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA....

July 31, 2010

Mitochondrial damage in the trabecular meshwork of patients with glaucoma

Experimental Paper of the Month

Mitochondrial damage in the trabecular meshwork of patients with glaucoma

Author(s): Izzotti A, Saccà SC, Longobardi M, Cartiglia C. Department of Health Sciences, University of Genoa, Genoa, Italy. izzotti@unige.it...

July 31, 2010

In patients with chronic angle-closure glaucoma and cataract, phacoemulsification with IOL implantation usually results in IOP control up to 2 years after surgery

Tip of the month

In patients with chronic angle-closure glaucoma and cataract, phacoemulsification with IOL implantation usually results in IOP control up to 2 years after surgery

The Science behind the Tip An anteriorly positioned and thickened lens plays an important role in the pathogenesis of anterior chamber shallowing...

June 30, 2010