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Not every ring scotoma is due to glaucoma
In advanced stages of glaucoma, patients may present with an annular scotoma, also known as ring...
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Relationship between Blood Pressure and Rates of Glaucomatous Visual Field Progression
Purpose: To examine the relationship between systemic arterial blood pressure (BP) and the rate...
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Comparison of Outcomes of Deep Sclerectomy, Canaloplasty, and Viscocanaloplasty: A Multi-Centred Study
Prcis: Deep sclerectomy (DS) and canaloplasty provide better intraocular pressure (IOP) control...
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Macular Oxygen Saturation in Glaucoma Using Retinal Oximetry of Visible Light Optical Coherence Tomography: A Pilot Study
Purpose: A cross-sectional pilot study to compare macular oxygen saturation (sO2) and associated...
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Childhood Glaucoma
SIG Corner Editor: Hana Abouzeid Chair: Esther Hoffmann Co-chair: Zeynep Aktas Childhood glaucoma...
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Avoid premature removal of the intraluminal suture in glaucoma drainage devices to minimize the risk of hypotony
While prolene suture removal is an effective method for reducing IOP at the slit-lamp, removing...
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Biomechanics-Function in Glaucoma: Improved Visual Field Predictions from IOP-Induced Neural Strains
Purpose: (1) To assess whether neural tissue structure and biomechanics could predict functional...
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Validation of a Visual Field Prediction Tool for Glaucoma: A Multicenter Study Involving Patients With Glaucoma in the United Kingdom
Purpose: A previously developed machine-learning approach with Kalman filtering technology...
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Fatal beauty: which cosmetics are your glaucoma patients using?
Colorism refers to the difference in social treatment between light-skinned and dark-skinned...
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The relationship between multiple deprivation and severity of glaucoma at diagnosis
BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with...
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Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients
Vitreous traction can cause artifacts that may obscure RNFL thinning, potentially leading to...
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Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis
Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee...
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Longitudinal effect of topical antiglaucoma medications on central corneal thickness
Author(s): Viswanathan D, Goldberg I, Graham SL Australian School of Advanced Medicine, Macquarie University, Sydney, Australia. BACKGROUND: To...
October 31, 2012
Intraocular pressure magnitude and variability as predictors of rates of structural change in non-human primate experimental glaucoma
Author(s): Gardiner SK, Fortune B, Wang L, Downs JC, Burgoyne CF Devers Eye Institute, Legacy Health, 1225 NE 2nd Ave., Portland, OR 97232, USA....
October 31, 2012
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Topical carbonic anhydrase inhibitors can cause damage in corneas with severe endothelial dysfunction
The Science behind the Tip The enzyme carbonic anhydrase is present in the corneal endothelium where it is involved in fluid transport (1). It thus...
September 30, 2012
Practical landmarks for visual field disability in glaucoma
Author(s): Saunders LJ, Russell RA, Crabb DP. City University London, London, UK. BACKGROUND/AIMS: To assess whether mean deviation (MD) from...
September 30, 2012
siRNA Silencing of Gene Expression in Trabecular Meshwork: RhoA siRNA Reduces IOP in Mice
Author(s): Liu Q, Wu K, Qiu X, Yang Y, Lin X, Yu M Few reports described efficient transfection in the trabecular meshwork (TM) in vivo. In the...
September 30, 2012
The Relationship Between Statin Use and Open-Angle Glaucoma
Author(s): Stein JD, Newman-Casey PA, Talwar N, Nan B, Richards JE, Musch DC. Department of Ophthalmology and Visual Sciences, University of...
July 31, 2012
Structural and functional abnormalities of retinal ganglion cells measured in vivo at the onset of optic nerve head surface change in experimental glaucoma
Author(s): Fortune B, Burgoyne CF, Cull GA, Reynaud J, Wang L. Devers Eye Institute, Discoveries in Sight Research Laboratories, Legacy Research...
July 31, 2012
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In patients with progressive normal tension glaucoma, the use of topical brimonidine may help to preserve visual function
The Science behind the Tip A recent study has shown that visual function is more likely to be preserved with brimonidine 2% than with timolol 0.5%...
June 30, 2012
Do patients with glaucoma have difficulty recognising faces?
Author(s): Glen FC, Crabb DP, Smith ND, Burton R, Garway-Heath DF. Department of Optometry and Visual Science, City University London, Northampton...
June 30, 2012
IOP induces upregulation of GFAP and MHC-II and microglia reactivity in mice retina contralateral to experimental glaucoma
Author(s): Gallego BI, Salazar JJ, de Hoz R, Rojas B, Ramírez AI, Salinas-Navarro M, Ortín-Martínez A, Valiente-Soriano FJ, Avilés-Trigueros M,...
June 30, 2012
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A dry eye can hamper visual field test interpretation
The Science behind the Tip During visual field (VF) testing the cornea of patients with severe dry eye condition can get dry to such an extent as...
May 31, 2012
Prevalence of cognitive impairment, depression, and anxiety symptoms among older adults with glaucoma
Author(s): Yochim BP, Mueller AE, Kane KD, Kahook MY. Department of Psychology, University of Colorado at Colorado Springs, Colorado Springs...
May 31, 2012
JNK2 and JNK3 are major regulators of axonal injury-induced retinal ganglion cell death
Author(s): Fernandes KA, Harder JM, Fornarola LB, Freeman RS, Clark AF, Pang IH, John SW, Libby RT. Flaum Eye Institute, University of Rochester...
May 31, 2012
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Laser peripheral iridotomy can reduce the intraocular pressure in pigment dispersion syndrome, but may not prevent glaucoma
The Science behind the Tip Nd-YAG laser peripheral iridotomy (PI) eliminates the reverse pressure gradient and intermittent posterior bowing of the...
April 30, 2012
The effect of thin, thick, and normal corneas on Goldmann intraocular pressure measurements and correction formulae in individual eyes
Author(s): Park SJ, Ang GS, Nicholas S, Wells AP. Eye Department, Wellington Hospital, Capital and Coast District Health Board, Wellington, New...
April 30, 2012
Cerebrospinal fluid exchange in the optic nerve in normal-tension glaucoma
Author(s): Killer HE, Miller NR, Flammer J, Meyer P, Weinreb RN, Remonda L, Jaggi GP. Kantonsspital Aarau, CH-5001 Aarau, Switzerland;...
April 30, 2012
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Gonioscopy should be performed using the minimal possible levels of illumination in order to reliably detect appositional angle closure
The Science behind the Tip Anterior chamber angle width varies dramatically with illumination (figure and video in ref. 1) (1,2). Visible...
March 31, 2012
Cataract surgery after trabeculectomy: the effect on trabeculectomy function
Author(s): Husain R, Liang S, Foster PJ, Gazzard G, Bunce C, Chew PT, Oen FT, Khaw PT, Seah SK, Aung T FRCS(Edin), Singapore National Eye Center,...
March 31, 2012
Multipotent Stem Cells from Trabecular Meshwork Become Phagocytic TM cells
Author(s): Du Y, Roh DS, Mann MM, Funderburgh ML, Funderburgh JL, Schuman JS. UPMC Eye Center, Ophthalmology and Visual Science Research Center,...
March 31, 2012
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Laser peripheral iridotomy does not usually result in long-term intraocular pressure control in patients with chronic angle-closure glaucoma
The Science behind the Tip The initial treatment of chronic angle-closure glaucoma is to undertake a laser peripheral iridotomy (PI) to prevent...
February 29, 2012
Outcomes of different management options for malignant glaucoma: a retrospective study
Author(s): Debrouwere V, Stalmans P, Van Calster J, Spileers W, Zeyen T, Stalmans I. Department of Ophthalmology, Kapucijnenvoer 33, 3000, Leuven,...
February 29, 2012
A New Approach to Assess Intracranial White Matter Abnormalities in Glaucoma Patients Changes of Fractional Anisotropy Detected by 3T Diffusion Tensor Imaging
Author(s): Engelhorn T, Michelson G, Waerntges S, Hempel S, El-Rafei A, Struffert T, Doerfler A. Department of Neuroradiology, University of...
February 29, 2012
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Trial lens artifacts can be easily distinguished from glaucomatous field defects
The Science behind the Tip False depressions due to a misaligned trial lens or a lens holder which was placed too far from the patient's eye are...
January 31, 2012
Optic nerve sheath diameter in normal-tension glaucoma patients
Author(s): Jaggi GP, Miller NR, Flammer J, Weinreb RN, Remonda L, Killer HE. Kantonsspital Aarau, Buchserstrasse, CH-5001 Aarau, Switzerland;...
January 31, 2012
Vision deficits precede structural losses in a mouse model of mitochondrial dysfunction and progressive retinal degeneration
Author(s): Laliberté AM, Macpherson TC, Micks T, Yan A, Hill KA Department of Biology, The University of Western Ontario, London, Ontario N6A 5B7,...
January 31, 2012