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  • Exfoliation SIG Corner

    SIG Corner Editor: Hana Abouzeid Chair: Gabor Hollo Co-chair: Anastasios G. Konstas The goal of this SIG is to increase ophthalmologists’ knowledge...

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    Exfoliation SIG Corner

    Exfoliation SIG Corner

    SIG Corner Editor: Hana Abouzeid Chair: Gabor Hollo Co-chair: Anastasios G. Konstas The goal of...

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  • IOP Reduction in Nonhuman Primates by Microneedle Injection of Drug-Free Hydrogel to Expand the Suprachoroidal Space

    Purpose: Expansion of the suprachoroidal space (SCS) by a hydrogel injection has been shown to reduce intraocular pressure (IOP) in rabbits as a...

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    IOP Reduction in Nonhuman Primates by Microneedle Injection of Drug-Free Hydrogel to Expand the Suprachoroidal Space

    IOP Reduction in Nonhuman Primates by Microneedle Injection of Drug-Free Hydrogel to Expand the Suprachoroidal Space

    Purpose: Expansion of the suprachoroidal space (SCS) by a hydrogel injection has been shown to...

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  • Relationship between Intraocular Pressure Fluctuation and Visual Field Progression Rates in the United Kingdom Glaucoma Treatment Study

    Purpose: To investigate whether intraocular pressure (IOP) fluctuation is associated independently with the rate of visual field (VF) progression...

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    Relationship between Intraocular Pressure Fluctuation and Visual Field Progression Rates in the United Kingdom Glaucoma Treatment Study

    Relationship between Intraocular Pressure Fluctuation and Visual Field Progression Rates in the United Kingdom Glaucoma Treatment Study

    Purpose: To investigate whether intraocular pressure (IOP) fluctuation is associated...

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  • Using anterior segment OCT to risk-stratify primary angle closure suspects

    Gonioscopy is the clinical standard for detecting patients at risk for primary angle closure glaucoma (PACG). However, anterior chamber angle...

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    Using anterior segment OCT to risk-stratify primary angle closure suspects

    Using anterior segment OCT to risk-stratify primary angle closure suspects

    Gonioscopy is the clinical standard for detecting patients at risk for primary angle closure...

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  • The relationship between multiple deprivation and severity of glaucoma at diagnosis

    BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with many individuals living with more than one illness....

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    The relationship between multiple deprivation and severity of glaucoma at diagnosis

    The relationship between multiple deprivation and severity of glaucoma at diagnosis

    BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with...

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  • Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee (4), Sung Ryul Shim (5), Ahnul Ha (6) 1 Department...

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    Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee...

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  • Angle Closure SIG

    SIG Corner Editor: Hana Abouzeid Chair: John Thygesen Co-chair: Gus Gazzard The goal of this SIG is to further the promotion of knowledge about the...

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    Angle Closure SIG

    Angle Closure SIG

    SIG Corner Editor: Hana Abouzeid Chair: John Thygesen Co-chair: Gus Gazzard The goal of this SIG...

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  • Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

    Author(s): Oana A Zeleznik ° (1,2), Jae H Kang ° (3,4), Jessica Lasky-Su (3,4), A Heather Eliassen (3,4,5,6), Lisa Frueh (3), Clary B Clish (7),...

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    Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

    Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

    Author(s): Oana A Zeleznik ° (1,2), Jae H Kang ° (3,4), Jessica Lasky-Su (3,4), A Heather...

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  • Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Vitreous traction can cause artifacts that may obscure RNFL thinning, potentially leading to misinterpretation of disease progression. Studies have...

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    Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Vitreous traction can cause artifacts that may obscure RNFL thinning, potentially leading to...

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  • Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists

    Author(s): Mário Lima-Fontes (1), Ana Faria-Pereira (1), Mariana Leuzinger-Dias (1), Marta Inês Silva (1), João Barbosa-Breda (1,2,3), Joana Araújo...

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    Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists

    Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists

    Author(s): Mário Lima-Fontes (1), Ana Faria-Pereira (1), Mariana Leuzinger-Dias (1), Marta Inês...

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  • Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure

    The mechanism is thought to be an idiosyncratic reaction to sulphonamides, similar to that which can occur with drugs such as topiramate. The...

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    Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure

    Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure

    The mechanism is thought to be an idiosyncratic reaction to sulphonamides, similar to that which...

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  • Cataract Surgery in Patients with Functioning Glaucoma Filtration Surgery

    The accelerated development of cataract is frequently seen in the years following glaucoma filtration surgery (1). Cataract surgery causes anterior...

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    Cataract Surgery in Patients with Functioning Glaucoma Filtration Surgery

    Cataract Surgery in Patients with Functioning Glaucoma Filtration Surgery

    The accelerated development of cataract is frequently seen in the years following glaucoma...

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The Effects of Optic Nerve Head Tilt on Visual Field Defects in Myopic Normal Tension Glaucoma: The Inter-eye Comparison Study

Clinical paper of the month

The Effects of Optic Nerve Head Tilt on Visual Field Defects in Myopic Normal Tension Glaucoma: The Inter-eye Comparison Study

Author(s): Choi JH (1), Han JC, Kee C 1 Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul,...

February 28, 2019

Identification of Candidate miRNA Biomarkers for Glaucoma

Experimental Paper of the Month

Identification of Candidate miRNA Biomarkers for Glaucoma

Author(s): Hindle AG1, Thoonen R2, Jasien JV (3), Grange RMH (1), Amin K (4), Wise J (4), Ozaki M (5), Ritch R (3), Malhotra R (2), Buys ES (1) 1...

February 28, 2019

Care Delivery SIG

SIG Corner

Care Delivery SIG

SIG Corner Editor: João Barbosa Breda Chair: Anton B. Hommer Co-chair: Gabor Holló Update on ongoing projects The goal of this SIG is to get a...

February 28, 2019

How to perform Goldmann applanation tonometry in patients with significant regular corneal astigmatism

Pearl

How to perform Goldmann applanation tonometry in patients with significant regular corneal astigmatism

Pearls Manager: Andrew Tatham When performing Goldmann applanation tonometry in patients with significant regular corneal astigmatism (>3...

February 20, 2019

Early bleb revision usually results in successful resolution of hypotony maculopathy after trabeculectomy with mitomycin C

Tip of the month

Early bleb revision usually results in successful resolution of hypotony maculopathy after trabeculectomy with mitomycin C

The Science behind the Tip Hypotony maculopathy is characterized by painless loss of vision usually more than three months after glaucoma...

January 31, 2019

Effects of Sex Hormones on Ocular Blood Flow and Intraocular Pressure in Primary Open-angle Glaucoma: A Review

Clinical paper of the month

Effects of Sex Hormones on Ocular Blood Flow and Intraocular Pressure in Primary Open-angle Glaucoma: A Review

Author(s): Patel P (1), Harris A (1), Toris C (2), Tobe L (1), Lang M (1), Belamkar A (1), Ng A (1), Verticchio Vercellin AC (3,4), Mathew S (1),...

January 31, 2019

Reduced Cerebrospinal Fluid Inflow to the Optic Nerve in Glaucoma

Experimental Paper of the Month

Reduced Cerebrospinal Fluid Inflow to the Optic Nerve in Glaucoma

Author(s): Mathieu E (1,2,3), Gupta N (1,2,3,4,5), Paczka-Giorgi LA (1,2), Zhou X (1,2), Ahari A (1,2), Lani R (1), Hanna J (1,2,3), Yücel YH...

January 31, 2019

Next Generation Partnership SIG

SIG Corner

Next Generation Partnership SIG

IG Corner Editor: João Barbosa Breda Chair: Gauti Jóhannesson Co-chairs: Esther Hoffmann, Francesco Oddone, Anthony Khawaja 1. Update on ongoing...

January 24, 2019

Children using topical corticosteroids for the treatment of allergic conjunctivitis must have their intraocular pressure regularly checked

Tip of the month

Children using topical corticosteroids for the treatment of allergic conjunctivitis must have their intraocular pressure regularly checked

The Science behind the Tip 30-40% of the population respond to topical steroids by increasing their IOP (1). A steroid response is commonly found...

December 31, 2018

Artificial intelligence and deep learning in ophthalmology

Clinical paper of the month

Artificial intelligence and deep learning in ophthalmology

Author(s): Ting DSW (1), Pasquale LR (2), Peng L (3), Campbell JP (4), Lee AY (5), Raman R (6), Tan GSW (7), Schmetterer L (7,8,9,10), Keane PA...

December 31, 2018

Residual vision activation and the brain-eye-vascular triad: Dysregulation, plasticity and restoration in low vision and blindness - a review

Experimental Paper of the Month

Residual vision activation and the brain-eye-vascular triad: Dysregulation, plasticity and restoration in low vision and blindness - a review

Author(s): Sabel BA (1), Flammer J (2), Merabet LB (3) 1 Institute of Medical Psychology, Medical Faculty, Otto-von-Guericke University of...

December 31, 2018

Exfoliative glaucoma is the most common type of secondary open angle glaucoma

Pearl

Exfoliative glaucoma is the most common type of secondary open angle glaucoma

Pearls Manager: Andrew Tatham It develops in approximately 15 to 26% of eyes with exfoliation syndrome within 5 years and frequently causes severe...

December 30, 2018

The results of trabeculectomy with mitomycin C are significantly improved in children with glaucoma secondary to juvenile idiopathic arthritis if they are on immune-modulatory treatment

Tip of the month

The results of trabeculectomy with mitomycin C are significantly improved in children with glaucoma secondary to juvenile idiopathic arthritis if they are on immune-modulatory treatment

The Science behind the Tip Juvenile idiopathic arthritis (JIA) is the most common systemic disease associated with childhood anterior uveitis....

November 30, 2018

Familial Risks of Glaucoma in the Population of Sweden

Clinical paper of the month

Familial Risks of Glaucoma in the Population of Sweden

Author(s): Li X (1), Sundquist J (1,2,3), Zöller B (1), Sundquist K (1,2,3) 1 Center for Primary Health Care Research, Lund University, Sweden. 2...

November 30, 2018

Mitochondrial DNA Variation and Disease Susceptibility in Primary Open-Angle Glaucoma

Experimental Paper of the Month

Mitochondrial DNA Variation and Disease Susceptibility in Primary Open-Angle Glaucoma

Author(s): Singh LN (1), Crowston JG (2), Lopez Sanchez MIG (2), Van Bergen NJ (2), Kearns LS (2), Hewitt AW (2,3), Yazar S (4,5), Mackey DA (4),...

November 30, 2018

Do you know how to stage an angle closure?

Pearl

Do you know how to stage an angle closure?

Pearls Manager: Andrew Tatham Primary Angle-Closure Suspect (PACS) - Two or more quadrants of iridotrabecular contact (lTC), normal IOP, no PAS, no...

November 23, 2018

Microperimetry may be a more sensitive method of detecting a small glaucomatous defect close to fixation, than standard automated perimetry and OCT analysis of the retinal nerve fibre layer (RNFL)

Tip of the month

Microperimetry may be a more sensitive method of detecting a small glaucomatous defect close to fixation, than standard automated perimetry and OCT analysis of the retinal nerve fibre layer (RNFL)

The Science behind the Tip Microperimetry is a form of fundus-tracking perimetry that can detect reduced retinal sensitivity close to fixation more...

October 31, 2018

The Magnitude of IOP Elevation Associated with Eye Rubbing

Clinical paper of the month

The Magnitude of IOP Elevation Associated with Eye Rubbing

Author(s): Turner DC (1), Girkin CA (2), Downs JC (3) 1 Department of Vision Sciences, School of Optometry, University of Alabama at Birmingham,...

October 31, 2018

Complement C3-Targeted Gene Therapy Restricts Onset and Progression of Neurodegeneration in Chronic Mouse Glaucoma

Experimental Paper of the Month

Complement C3-Targeted Gene Therapy Restricts Onset and Progression of Neurodegeneration in Chronic Mouse Glaucoma

Author(s): Bosco A(1), Anderson SR(2), Breen KT(2), Romero CO(2), Steele MR(2), Chiodo VA(3), Boye SL(3), Hauswirth WW(3), Tomlinson S(4), Vetter...

October 31, 2018

When to perform a prophylactic iridotomy?

Pearl

When to perform a prophylactic iridotomy?

Pearls Manager: Andrew Tatham An international group of experts reached a consensus that 2 quadrants or more of ITC is an indication for...

October 22, 2018

A glaucoma drainage device may be more effective than trabeculectomy in lowering IOP after keratoplasty, but is more likely to result in graft failure

Tip of the month

A glaucoma drainage device may be more effective than trabeculectomy in lowering IOP after keratoplasty, but is more likely to result in graft failure

The Science behind the Tip A well-controlled intraocular pressure (IOP) after penetrating keratoplasty (PK) is essential for graft survival and to...

September 30, 2018

Structural reversal of disc cupping after trabeculectomy alters Bruch's membrane opening-based parameters to assess neuroretinal rim

Clinical paper of the month

Structural reversal of disc cupping after trabeculectomy alters Bruch's membrane opening-based parameters to assess neuroretinal rim

Author(s): Gietzelt C (1), Lemke J (1), Schaub F (1), Hermann MM (1), Dietlein TS (1), Cursiefen C (1), Enders P (2), Heindl LM (1) 1 Department of...

September 30, 2018

Genome-wide association study of intraocular pressure uncovers new pathways to glaucoma

Experimental Paper of the Month

Genome-wide association study of intraocular pressure uncovers new pathways to glaucoma

Author(s): MacGregor S (1), Ong JS (2), An J (2), Han X (2), Zhou T (3), Siggs OM (3), Law MH (2), Souzeau E (3), Sharma S (3), Lynn DJ (4,5,6),...

September 30, 2018

Tolerable rates of visual field progression in a population-based sample of patients with glaucoma

Clinical paper of the month

Tolerable rates of visual field progression in a population-based sample of patients with glaucoma

Author(s): Salonikiou A (1), Founti P (1,2), Kilintzis V (1), Antoniadis A (1), Anastasopoulos E (1), Pappas T (1), Raptou A (1), Topouzis F (1) 1...

July 31, 2018

Nogo-A inactivation improves visual plasticity and recovery after retinal injury

Experimental Paper of the Month

Nogo-A inactivation improves visual plasticity and recovery after retinal injury

Author(s): Mdzomba JB (1), Jordi N (2), Rodriguez L (1), Joly S (1), Bretzner F (3), Pernet V (4) 1 CUO-Recherche, Centre de recherche du CHU de...

July 31, 2018