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Identification of Optic Nerve–Related Biomarkers in Primary Open-Angle Glaucoma Based on Comprehensive Bioinformatics and Mendelian Randomization
Purpose: Glaucoma is the primary cause of permanent vision loss worldwide. However, the...
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Quality of Life and Primary Open-Angle Glaucoma in the Ocular Hypertension Treatment Study
Importance: If preperimetric glaucoma reduces patient-reported vision-related quality of life...
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Fatal beauty: which cosmetics are your glaucoma patients using?
Colorism refers to the difference in social treatment between light-skinned and dark-skinned...
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The relationship between multiple deprivation and severity of glaucoma at diagnosis
BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with...
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Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank
Author(s): Oana A Zeleznik ° (1,2), Jae H Kang ° (3,4), Jessica Lasky-Su (3,4), A Heather...
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Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients
Vitreous traction can cause artifacts that may obscure RNFL thinning, potentially leading to...
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Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis
Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee...
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Angle Closure SIG
SIG Corner Editor: Hana Abouzeid Chair: John Thygesen Co-chair: Gus Gazzard The goal of this SIG...
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Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists
Author(s): Mário Lima-Fontes (1), Ana Faria-Pereira (1), Mariana Leuzinger-Dias (1), Marta Inês...
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Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure
The mechanism is thought to be an idiosyncratic reaction to sulphonamides, similar to that which...
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Cataract Surgery in Patients with Functioning Glaucoma Filtration Surgery
The accelerated development of cataract is frequently seen in the years following glaucoma...
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Incidence of glaucomatous visual field loss: a ten-year follow-up from the Rotterdam Study
Author(s): Czudowska MA, Ramdas WD, Wolfs RC, Hofman A, De Jong PT, Vingerling JR, Jansonius NM Department of Epidemiology, Erasmus Medical Center,...
October 31, 2010
Functional MRI signal changes in primary visual cortex corresponding to the central normal visual field of patients with primary open-angle glaucoma
Author(s): Qing G, Zhang S, Wang B, Wang N Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology...
October 31, 2010
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If conservative measures are unsuccessful in the management of malignant glaucoma, phaco with IOL combined with posterior capsulotomy and anterior vitrectomy usually is
The Science behind the Tip Malignant glaucoma in a phakic eye typically follows incisional surgery for primary angle-closure glaucoma. Shallowing...
September 30, 2010
Anthropometric measures and their relation to incident primary open-angle glaucoma
Author(s): Pasquale LR, Willett WC, Rosner BA, Kang JH Department of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear Infirmary,...
September 30, 2010
Current approaches and future prospects for stem cell rescue and regeneration of the retina and optic nerve
Author(s): Dahlmann-Noor A, Vijay S, Jayaram H, Limb A, Khaw PT. The 3 most common causes of visual impairment and legal blindness in developed...
September 30, 2010
Effect of sleeping in a head-up position on intraocular pressure in patients with glaucoma
Author(s): Buys YM, Alasbali T, Jin YP, Smith M, Gouws P, Geffen N, Flanagan JG, Shapiro CM, Trope GE Department of Ophthalmology and Vision...
August 31, 2010
Genome-wide association study of normal tension glaucoma: common variants in SRBD1 and ELOVL5 contribute to disease susceptibility
Author(s): Writing Committee fot the Normal Tension Glaucoma Genetic Study Group of Japan Glaucoma Society, Meguro A, Inoko H, Ota M, Mizuki N,...
August 31, 2010
Clinical classification of childhood glaucomas
Author(s): Yeung HH, Walton DS Department of Pediatrics, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA....
July 31, 2010
Mitochondrial damage in the trabecular meshwork of patients with glaucoma
Author(s): Izzotti A, Saccà SC, Longobardi M, Cartiglia C. Department of Health Sciences, University of Genoa, Genoa, Italy. izzotti@unige.it...
July 31, 2010
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In patients with chronic angle-closure glaucoma and cataract, phacoemulsification with IOL implantation usually results in IOP control up to 2 years after surgery
The Science behind the Tip An anteriorly positioned and thickened lens plays an important role in the pathogenesis of anterior chamber shallowing...
June 30, 2010
Effect of patient's life expectancy on the cost-effectiveness of treatment for ocular hypertension
Author(s): Kymes SM, Plotzke MR, Kass MA, Boland MV, Gordon MO OBJECTIVE: To assess the influence of expected life span on the cost-effectiveness...
June 30, 2010
Metabolic vulnerability disposes retinal ganglion cell axons to dysfunction in a model of glaucomatous degeneration
Author(s): Baltan S, Inman DM, Danilov CA, Morrison RS, Calkins DJ, Horner PJ. We tested the hypothesis that glaucoma disrupts electrophysiological...
June 30, 2010
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Measurement of central corneal thickness is essential to ensure optimal management of glaucoma patients
The Science behind the Tip The measurement of central corneal thickness (CCT) has emerged as an important parameter to determine in all patients...
May 31, 2010
Delaying Treatment of Ocular Hypertension: the Ocular Hypertension Treatment Study
Author(s): Michael A. Kass, MD; Mae O. Gordon, PhD; Feng Gao, PhD; Dale K. Heuer, MD; Eve J. Higginbotham, MD; Chris A. Johnson, PhD; John K....
May 31, 2010
Neuroprotective Effects of Intravitreal Mesenchymal Stem Cell Transplantation in Experimental Glaucoma
Author(s): Thomas V. Johnson(1,2,3) Natalie D. Bull(1,2) David P. Hunt(1), Nephtali Marina(1), Stanislav I. Tomarev(3), Keith R. Martin(1) Centre...
May 31, 2010
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Disc Haemorrhages
The Science behind the Tip Although described most commonly in normal tension glaucoma, optic disc haemorrhages may occur in all forms of glaucoma....
April 30, 2010
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When should neuroradiological imaging be undertaken in patients with normal tension glaucoma?
The Science behind the Tip Clinicians must remain vigilant to detect intracranial pathology in patients with normal tension glaucoma. Most patients...
March 31, 2010
Simvastatin and Disease Stabilization in Normal Tension Glaucoma: A Cohort Study.
Author(s): Leung DY, Li FC, Kwong YY, Tham CC, Chi SC, Lam DS. Department of Ophthalmology and Visual Sciences, The Chinese University of Hong...
March 31, 2010
Episcleral Venous Pressure Responses to Topical Nitroprusside and N-Nitro-L-arginine Methyl Ester.
Author(s): Zamora DO, Kiel JW. Department of Ophthalmology, University of Texas Health Science Center, San Antonio, Texas. PURPOSE: To determine...
March 31, 2010
Cerebrospinal Fluid Pressure in Glaucoma A Prospective Study.
Author(s): Ren R, Jonas JB, Tian G, Zhen Y, Ma K, Li S, Wang H, Li B, Zhang X, Wang N Beijing Institute of Ophthalmology, Beijing Tongren Eye...
February 28, 2010
Hemoglobin expression and regulation in glaucoma: insights into retinal ganglion cell oxygenation.
Author(s): Tezel G, Yang X, Luo C, Cai J, Kain AD, Powell DW, Kuehn MH, Pierce WM Department of Ophthalmology and Visual Sciences, University of...
February 28, 2010
Prediction of glaucomatous visual field loss by extrapolation of linear trends
Author(s): Bengtsson B, Patella VM, Heijl A Departments of Clinical Sciences and Ophthalmology, Lund University, Malmö University Hospital,...
January 31, 2010
Ocular hypertension impairs optic nerve axonal transport leading to progressive retinal ganglion cell degeneration
Author(s): Salinas-Navarro M, Alarcón-Martínez L, Valiente-Soriano FJ, Jiménez-López M, Mayor-Torroglosa S, Avilés-Trigueros M, Villegas-Pérez MP,...
January 31, 2010
Increased likelihood of glaucoma at the same screening intraocular pressure in subjects with pseudoexfoliation: the Thessaloniki Eye Study
Author(s): Topouzis F, Harris A, Wilson MR, Koskosas A, Founti P, Yu F, Anastasopoulos E, Pappas T, Coleman AL Department of Ophthalmology, School...
November 30, 2009
Complex antibody profile changes in an experimental autoimmune glaucoma animal model
Author(s): Joachim SC, Grus FH, Kraft D, White-Farrar K, Barnes G, Barbeck M, Ghanaati S, Cao S, Li B, Wax MB Experimental Ophthalmology,...
October 31, 2009