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F4H5 Alleviates Increased Outflow Resistance Induced by Emulsified Silicone Oil In Vitro
Purpose: The purpose of this study was to investigate the effect of emulsified silicone oil on...
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The scleral spur
The scleral spur is a ring-shaped structure, primarily collagen with 5% elastin (1), providing...
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Neuroprotection in Glaucoma: Investigational, Complementary to IOP-Lowering
Tip: Neuroprotection in glaucoma is investigational and may be considered only as an adjunct,...
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Evaluating High Intraocular Pressure Criteria for Failure in Glaucoma Surgery: Impact on Estimated Success and Visual Field Rates
Purpose: Review high intraocular pressure (IOP) thresholds used as failure criteria in glaucoma...
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Gonioscopy is always essential
Angle closure is defined by iridotrabecular contact of ≥180° (1) and the presence or development...
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Association of Blood Pressure and Retinal Nerve Fiber Layer Rates of Thinning in Patients with Moderate to Advanced Glaucoma
Objective: To investigate the influence of baseline blood pressure (BP) on retinal nerve fiber...
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Aqueous Humor Antioxidants in Glaucoma: Correlations With Subtypes, Intraocular Pressure, and Medication Use - A Prospective Study
Purpose: To investigate the correlations between aqueous humor total antioxidant capacity (TAC)...
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Care Delivery
SIG Corner Editor: Hana Abouzeid Chair: Anton B. Hommer Co-chair: Gabor Hollo Update on ongoing...
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Comparative Study of Early Safety and Effectiveness Outcomes of the PreserFlo MicroShunt with and without an Intraluminal Suture Stent
Objective: To assess the early safety and effectiveness outcomes of the PreserFlo MicroShunt with...
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Iris Crypts Could Reduce the Chance of Angle Closure: A Computational Biomechanics Study Derived From Clinical and Human Iris Data
Purpose: To investigate the effect of crypts during pupil constriction and dilation on the...
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Glaucoma drainage devices - Is the Paul glaucoma implant suitable for children with glaucoma?
Only a few studies exist on the Paul glaucoma device in children with glaucoma. Compared to Ahmed...
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Comparison of Methods to Deliver Mitomycin C in Trabeculectomy Surgery: a Systematic Review and Meta-analysis
Purpose: Compare different methods to deliver Mitomycin C (MMC) in trabeculectomy surgery....
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Childhood glaucoma
Congenital glaucoma occurs in about 1 in 12-18,000 births among white Europeans. Incidence can be 5 to 10 times higher if consanguinity of parents...
May 21, 2026
Timeless Tips to remember
Raised intraocular pressure (IOP) and secondary glaucoma due to underlying uveitis is a well-acknowledged phenomenon (1). The clinician should...
May 21, 2026
NeuProIO: A dual-action solid drug nanoparticle topical formulation for simultaneous intraocular pressure reduction and neuroprotection for glaucoma
Abstract: Glaucoma is a leading cause of irreversible blindness, primarily due to elevated intraocular pressure (IOP) that damages the retina and...
May 21, 2026
Treatment – General principles
The only proven method of preserving visual function is to reduce the intraocular pressure (IOP). EGS Guidelines, 6th Edition, Page 159 Pearls...
May 21, 2026
Long-term Persistent Angle Closure and Anatomic Changes after Laser Iridotomy in Suspected Primary Angle-Closure
Purpose: To evaluate the proportion of patients with, and anatomic predictors of, persistent angle closure 5 years after laser peripheral iridotomy...
May 21, 2026
Local toxicity of topical treatment: the role of preservatives
Therapeutic options to reduce OSD include preservative-free or BAC-free medication, decreasing the number of eye drops (e.g., by using fixed...
April 22, 2026
Laser peripheral iridotomy
Indications: Angle closure disease: high risk Primary Angle Closure Suspect, Primary Angle Closure [and] Primary Angle Closure Glaucoma; treatment...
April 22, 2026
In Vivo Comparison of Intracameral and Intravitreal Implantation of a Timolol Maleate Miniaturized Injectable Delivery System Device
Purpose: Miniaturized injectable delivery system (MIDS) devices engineered for zero-order release of timolol maleate are evaluated for intracameral...
April 20, 2026
Artificial intelligence-based glaucoma screening in primary care: a cross-sectional study and economic viability analysis of an ongoing trial
Background: Glaucoma is a leading cause of blindness and is often undiagnosed. Owing to novel artificial intelligence (AI) technology,...
April 20, 2026
Not all patients diagnosed with pseudoexfoliation will develop glaucoma; however, in those with concurrent ocular hypertension, more intensive management is needed.
Pseudoexfoliation (PEX) is a common disorder and the most common cause of secondary glaucoma. Despite this, not all subjects with PEX will develop...
April 20, 2026
Prognostic factors associated with progression of open-angle glaucoma in adults
Background: Glaucoma is the leading cause of irreversible blindness globally, and the second leading cause of blindness in high-income countries....
March 22, 2026
World Glaucoma Week 2026
Many european colleagues have engaged those around them to raise awareness about glaucoma during the World Glaucoma Week 2026. Here are some of the...
March 22, 2026
Prof. Carlo Traverso awarded the 2026 Manfred Bootz Prize
Professor Carlo Traverso has been awarded the 2026 Manfred Bootz Prize, a prestigious recognition dedicated to individuals who have made...
March 19, 2026
Prof. Dr. Augusto Azuara-Blanco has received the AGS International Scholar Award from the American Glaucoma Society.
We are delighted to announce that Prof. Dr. Augusto Azuara-Blanco has received the AGS International Scholar Award from the American Glaucoma...
March 19, 2026
Actin depolymerization promotes axon regeneration by restoring axonal mitochondrial transport in mouse models of optic neuropathy
Adult mammalian central nervous system (CNS) axons do not spontaneously regenerate after injury. We recently identified multiple genes that promote...
March 15, 2026
Comparing the utility of retinal nerve fiber layer and ganglion cell inner plexiform layer OCT changes to detect glaucoma progression
Purpose: Measure and compare the rates of circumpapillary retinal nerve fiber layer (cpRNFL) and macular ganglion cell—inner plexiform layer...
March 15, 2026
Visual loss after initiation of netarsudil/latanoprost: have you considered RECE?
Netarsudil may disrupt epithelial barrier function and alter the epithelial basement membrane [1], potentially allowing stromal fluid to accumulate...
March 15, 2026
Childhood glaucoma
Certain diagnostic criteria likely carry more weight than others, e.g. Haab striae, axial length. […] Haab striae are a strong indicator of...
March 14, 2026
Anterior segment imaging techniques
Anterior chamber angle imaging devices can be useful to identify the iris configuration of a narrow angle, to assess the influence of the lens, for...
March 14, 2026
Laser trabeculoplasty
ALT and SLT have the same IOP-lowering efficacy. Laser trabeculoplasty is initially effective in 80 to 85% of treated eyes with a mean IOP...
February 19, 2026
Choosing wisely / Things to avoid
Do not use MIGS on a rapidly worsening patient. MIGS are mostly used to offer the opportunity to mildly lower the IOP and decrease medications in...
February 19, 2026
Influence of intraocular pressure on clinical decision-making in glaucoma management
Importance: Understanding of intraocular pressure (IOP) as a continuous risk factor for glaucoma has evolved over time, and IOP reduction is widely...
February 17, 2026
IOP control should not come at the expense of the ocular surface
Topical IOP-lowering medications are widely used and effective in glaucoma management, but long-term exposure—particularly to preserved, multi-drug...
February 17, 2026
Circulating eNAMPT in glaucoma: A semi-quantitative plasma analysis before and after nicotinamide supplementation
Purpose: Glaucoma is characterized by progressive retinal ganglion cell degeneration. Nicotinamide supplementation has demonstrated neuroprotective...
February 17, 2026
Start with monotherapy
The greatest reduction of IOP is obtained with PGAs, followed by non-selective β-blockers, Rho-kinase inhibitors, alpha-adrenergic agonists,...
January 21, 2026