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Comparison of Methods to Deliver Mitomycin C in Trabeculectomy Surgery: a Systematic Review and Meta-analysis
Purpose: Compare different methods to deliver Mitomycin C (MMC) in trabeculectomy surgery....
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Aqueous Humor Antioxidants in Glaucoma: Correlations With Subtypes, Intraocular Pressure, and Medication Use - A Prospective Study
Purpose: To investigate the correlations between aqueous humor total antioxidant capacity (TAC)...
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Optic Disc Microvasculature Reduction and Visual Field Progression in Primary Open-Angle Glaucoma
Purpose: To investigate the relationship between optic disc vessel density (ODVD) reduction and...
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Consider cotton wool spots as potential triggers for (non-glaucomatous) nerve fibre bundle defects
It may be tempting to make a glaucoma diagnosis in the presence of a nerve fibre bundle defect...
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Risk Score Predicting Primary Open-Angle Glaucoma Patients With Vascular Predisposition
Purpose: We tested the hypothesis that a questionnaire-based risk score predicts the prevalence...
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Not every ring scotoma is due to glaucoma
In advanced stages of glaucoma, patients may present with an annular scotoma, also known as ring...
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Relationship between Blood Pressure and Rates of Glaucomatous Visual Field Progression
Purpose: To examine the relationship between systemic arterial blood pressure (BP) and the rate...
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Comparison of Outcomes of Deep Sclerectomy, Canaloplasty, and Viscocanaloplasty: A Multi-Centred Study
Prcis: Deep sclerectomy (DS) and canaloplasty provide better intraocular pressure (IOP) control...
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Macular Oxygen Saturation in Glaucoma Using Retinal Oximetry of Visible Light Optical Coherence Tomography: A Pilot Study
Purpose: A cross-sectional pilot study to compare macular oxygen saturation (sO2) and associated...
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Childhood Glaucoma
SIG Corner Editor: Hana Abouzeid Chair: Esther Hoffmann Co-chair: Zeynep Aktas Childhood glaucoma...
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Avoid premature removal of the intraluminal suture in glaucoma drainage devices to minimize the risk of hypotony
While prolene suture removal is an effective method for reducing IOP at the slit-lamp, removing...
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Biomechanics-Function in Glaucoma: Improved Visual Field Predictions from IOP-Induced Neural Strains
Purpose: (1) To assess whether neural tissue structure and biomechanics could predict functional...
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Lifetime Risk of Blindness in Open-Angle Glaucoma
Author(s): Peters D, Bengtsson B, Heijl A Department of Ophthalmology, Lund University, Skåne University Hospital, Malmö, Sweden. Electronic...
October 31, 2013
Immune response against ocular tissues after immunization with optic nerve antigens in a model of autoimmuneglaucoma
Author(s): Joachim SC, Reinehr S, Kuehn S, Laspas P, Gramlich OW, Kuehn M, Tischoff I, von Pein HD, Dick HB, Grus FH Experimental Eye Research...
October 31, 2013
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The measurement of retinal nerve fibre thickness is helpful in determining which patients with ocular hypertension will develop glaucoma
The Science behind the Tip In patients with ocular hypertension, moderate to severe retinal nerve fibre layer (RNFL) atrophy at baseline has been...
September 30, 2013
The Ahmed Versus Baerveldt Study: Three-Year Treatment Outcomes
Author(s): Christakis PG, Tsai JC, Kalenak JW, Zurakowski D, Cantor LB, Kammer JA, Ahmed II. Department of Ophthalmology and Vision Sciences,...
September 30, 2013
Onset and Progression of Peripapillary Retinal Nerve Fiber Layer (RNFL) Retardance Changes Occur Earlier than RNFL Thickness Changes in Experimental Glaucoma
Author(s): Fortune B, Burgoyne CF, Cull G, Reynaud J, Wang L. Devers Eye Institute, Legacy Research Institute, 1225 NE 2nd Avenue, 3rd Floor,...
September 30, 2013
Rho-associated kinase inhibitors: A novel glaucoma therapy
Author(s): Inoue T, Tanihara H. Department of Ophthalmology, Faculty of Life Sciences, Kumamoto University, 1-1-1, Honjo, Kumamoto, Japan....
July 31, 2013
Ocular Rigidity, Outflow facility, Ocular Pulse Amplitude and Pulsatile Ocular Blood Flow in Open AngleGlaucoma; a manometric study
Author(s): Dastiridou AI, Tsironi EE, Tsilimbaris M, Ginis H, Karyotakis N, Cholevas P, Androudi S, Pallikaris IG. Ophthalmology Department,...
July 31, 2013
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Post-traumatic angle-recession glaucoma is difficult to manage and surgical intervention is often required
The Science behind the Tip Anterior chamber angle recession is the commonest physical sign of previous blunt trauma to the eye. Raised intraocular...
June 30, 2013
Prevalence and Severity of Undetected Manifest Glaucoma: Results from the Early Manifest Glaucoma Trial Screening
Author(s): Heijl A, Bengtsson B, Oskarsdottir SE. Lund University, Department of Clinical Sciences Malmö, Ophthalmology, Skåne University Hospital,...
June 30, 2013
Acetylcholinesterase inhibition promotes retinal vasoprotection and increases ocular blood flow in experimental glaucoma
Author(s): Almasieh M, Macintyre JN, Pouliot M, Casanova C, Vaucher E, Kelly ME, Di Polo A. Department of Pathology and Cell Biology and Groupe de...
June 30, 2013
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The use of Ginkgo biloba may increase the risk of bleeding
The Science behind the Tip Extracts of the leaves of the Asiatic tree Ginkgo biloba (GBE) provide protection against mitochondrial oxidative damage...
May 31, 2013
The eye and the heart
Author(s): Flammer J, Konieczka K, Bruno R M, Virdis A, Flammer A J, Taddei S The vasculature of the eye and the heart share several common...
May 31, 2013
Reduction in Blood Glutathione Levels Occurs Similarly in Patients with Primary-Open Angle or Normal Tension Glaucoma
Author(s): Gherghel D, Mroczkowska S, Qin L Vascular Research Laboratory, Ophthalmic Research Group, Aston University, School of Life and Health...
May 31, 2013
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If surgery is required to control IOP in a patient with nanophthalmos, phacoemulsification with IOL implantation is a good option, but the complication rate is high
The Science behind the Tip Nanophthalmos, small eye-big trouble, is a form of microophthalmos which is not accompanied by other congenital...
April 30, 2013
How Does Glaucoma Look?: Patient Perception of Visual Field Loss
Author(s): Crabb DP, Smith ND, Glen FC, Burton R, Garway-Heath DF Department of Optometry and Visual Science, City University London, London,...
April 30, 2013
Tissue engineering the retinal ganglion cell nerve fiber layer
Author(s): Kador KE, Montero RB, Venugopalan P, Hertz J, Zindell AN, Valenzuela DA, Uddin MS, Lavik EB, Muller KJ, Andreopoulos FM, Goldberg JL...
April 30, 2013
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Indefinite use of cycloplegics can be the last resort when surgery for malignant glaucoma has failed
The Science behind the Tip Malignant glaucoma or aqueous misdirection is a rare but feared complication of anterior segment surgery. It occurs in...
March 31, 2013
Treatment Outcomes in Malignant Glaucoma
Author(s): Dave P, Senthil S, Rao HL, Garudadri CS. L. V. Prasad Eye Institute, Hyderabad, India. PURPOSE: To report treatment outcomes in...
March 31, 2013
Discovery of novel human aquaporin-1 blockers
Author(s): Seeliger D, Zapater C, Krenc D, Haddoub R, Flitsch S, Beitz E, Cerdà J, de Groot BL. Human aquaporin-1 (hAQP1) is a water channel found...
March 31, 2013
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Young men of European ancestry with angle-closure require thorough investigation
The Science behind the Tip Primary angle closure glaucoma is rare in younger white adults, with an estimated age specific prevalence of 0.02% for...
February 28, 2013
Protective effect of lipoic acid against oxidative stress is mediated by Keap1/Nrf2-dependent heme oxygenase-1 induction in the RGC-5 cell line
Author(s): Koriyama Y, Nakayama Y, Matsugo S, Kato S. Department of Molecular Neurobiology, Graduate School of Medicine. Electronic address:...
February 28, 2013
Balance control in glaucoma
Author(s): Kotecha A, Richardson G, Chopra R, Fahy RT, Garway-Heath DF, Rubin GS Department of Visual Neuroscience, University College London (UCL)...
January 31, 2013
A new safety concern for glaucoma treatment demonstrated by mass spectrometry imaging of benzalkonium chloride distribution in the eye, an experimental study in rabbits
Author(s): Brignole-Baudouin F, Desbenoit N, Hamm G, Liang H, Both JP, Brunelle A, Fournier I, Guerineau V, Legouffe R, Stauber J, Touboul D,...
January 31, 2013
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Intravitreal steroids should be used with caution in patients with glaucoma
The Science behind the Tip In recent years it has become common practice to inject steroids into the vitreous to reduce macular oedema or ocular...
December 31, 2012
Factors that influence standard automated perimetry test results in glaucoma: test reliability, technician experience, time of day, and season
Author(s): Junoy Montolio FG, Wesselink C, Gordijn M, Jansonius NM Department of Ophthalmology, University Medical Center Groningen, University of...
December 31, 2012