• Not every ring scotoma is due to glaucoma

    In advanced stages of glaucoma, patients may present with an annular scotoma, also known as ring scotoma, where the retinal sensitivity is...

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    Not every ring scotoma is due to glaucoma

    Not every ring scotoma is due to glaucoma

    In advanced stages of glaucoma, patients may present with an annular scotoma, also known as ring...

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  • Relationship between Blood Pressure and Rates of Glaucomatous Visual Field Progression

    Purpose: To examine the relationship between systemic arterial blood pressure (BP) and the rate of change in standard automated perimetry (SAP) in...

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    Relationship between Blood Pressure and Rates of Glaucomatous Visual Field Progression

    Relationship between Blood Pressure and Rates of Glaucomatous Visual Field Progression

    Purpose: To examine the relationship between systemic arterial blood pressure (BP) and the rate...

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  • Comparison of Outcomes of Deep Sclerectomy, Canaloplasty, and Viscocanaloplasty: A Multi-Centred Study

    Prcis: Deep sclerectomy (DS) and canaloplasty provide better intraocular pressure (IOP) control than viscocanalostomy. DS required less glaucoma...

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    Comparison of Outcomes of Deep Sclerectomy, Canaloplasty, and Viscocanaloplasty: A Multi-Centred Study

    Comparison of Outcomes of Deep Sclerectomy, Canaloplasty, and Viscocanaloplasty: A Multi-Centred Study

    Prcis: Deep sclerectomy (DS) and canaloplasty provide better intraocular pressure (IOP) control...

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  • Macular Oxygen Saturation in Glaucoma Using Retinal Oximetry of Visible Light Optical Coherence Tomography: A Pilot Study

    Purpose: A cross-sectional pilot study to compare macular oxygen saturation (sO2) and associated clinical measurements between normal and glaucoma...

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    Macular Oxygen Saturation in Glaucoma Using Retinal Oximetry of Visible Light Optical Coherence Tomography: A Pilot Study

    Macular Oxygen Saturation in Glaucoma Using Retinal Oximetry of Visible Light Optical Coherence Tomography: A Pilot Study

    Purpose: A cross-sectional pilot study to compare macular oxygen saturation (sO2) and associated...

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  • Childhood Glaucoma

    SIG Corner Editor: Hana Abouzeid Chair: Esther Hoffmann Co-chair: Zeynep Aktas Childhood glaucoma is a rare but severe ocular condition that can...

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    Childhood Glaucoma

    Childhood Glaucoma

    SIG Corner Editor: Hana Abouzeid Chair: Esther Hoffmann Co-chair: Zeynep Aktas Childhood glaucoma...

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  • Avoid premature removal of the intraluminal suture in glaucoma drainage devices to minimize the risk of hypotony

    While prolene suture removal is an effective method for reducing IOP at the slit-lamp, removing it too early can lead to postoperative hypotony and...

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    Avoid premature removal of the intraluminal suture in glaucoma drainage devices to minimize the risk of hypotony

    Avoid premature removal of the intraluminal suture in glaucoma drainage devices to minimize the risk of hypotony

    While prolene suture removal is an effective method for reducing IOP at the slit-lamp, removing...

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  • Biomechanics-Function in Glaucoma: Improved Visual Field Predictions from IOP-Induced Neural Strains

    Purpose: (1) To assess whether neural tissue structure and biomechanics could predict functional loss in glaucoma; (2) To evaluate the importance...

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    Biomechanics-Function in Glaucoma: Improved Visual Field Predictions from IOP-Induced Neural Strains

    Biomechanics-Function in Glaucoma: Improved Visual Field Predictions from IOP-Induced Neural Strains

    Purpose: (1) To assess whether neural tissue structure and biomechanics could predict functional...

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  • Validation of a Visual Field Prediction Tool for Glaucoma: A Multicenter Study Involving Patients With Glaucoma in the United Kingdom

    Purpose: A previously developed machine-learning approach with Kalman filtering technology accurately predicted the disease trajectory for patients...

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    Validation of a Visual Field Prediction Tool for Glaucoma: A Multicenter Study Involving Patients With Glaucoma in the United Kingdom

    Validation of a Visual Field Prediction Tool for Glaucoma: A Multicenter Study Involving Patients With Glaucoma in the United Kingdom

    Purpose: A previously developed machine-learning approach with Kalman filtering technology...

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  • Fatal beauty: which cosmetics are your glaucoma patients using?

    Colorism refers to the difference in social treatment between light-skinned and dark-skinned people. This sociological concept is a result of...

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    Fatal beauty: which cosmetics are your glaucoma patients using?

    Fatal beauty: which cosmetics are your glaucoma patients using?

    Colorism refers to the difference in social treatment between light-skinned and dark-skinned...

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  • The relationship between multiple deprivation and severity of glaucoma at diagnosis

    BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with many individuals living with more than one illness....

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    The relationship between multiple deprivation and severity of glaucoma at diagnosis

    The relationship between multiple deprivation and severity of glaucoma at diagnosis

    BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with...

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  • Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Vitreous traction can cause artifacts that may obscure RNFL thinning, potentially leading to misinterpretation of disease progression. Studies have...

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    Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Vitreous traction can cause artifacts that may obscure RNFL thinning, potentially leading to...

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  • Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee (4), Sung Ryul Shim (5), Ahnul Ha (6) 1 Department...

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    Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee...

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Rho-associated kinase inhibitors: A novel glaucoma therapy

Clinical paper of the month

Rho-associated kinase inhibitors: A novel glaucoma therapy

Author(s): Inoue T, Tanihara H. Department of Ophthalmology, Faculty of Life Sciences, Kumamoto University, 1-1-1, Honjo, Kumamoto, Japan....

July 31, 2013

Ocular Rigidity, Outflow facility, Ocular Pulse Amplitude and Pulsatile Ocular Blood Flow in Open AngleGlaucoma; a manometric study

Experimental Paper of the Month

Ocular Rigidity, Outflow facility, Ocular Pulse Amplitude and Pulsatile Ocular Blood Flow in Open AngleGlaucoma; a manometric study

Author(s): Dastiridou AI, Tsironi EE, Tsilimbaris M, Ginis H, Karyotakis N, Cholevas P, Androudi S, Pallikaris IG. Ophthalmology Department,...

July 31, 2013

Post-traumatic angle-recession glaucoma is difficult to manage and surgical intervention is often required

Tip of the month

Post-traumatic angle-recession glaucoma is difficult to manage and surgical intervention is often required

The Science behind the Tip Anterior chamber angle recession is the commonest physical sign of previous blunt trauma to the eye. Raised intraocular...

June 30, 2013

Prevalence and Severity of Undetected Manifest Glaucoma: Results from the Early Manifest Glaucoma Trial Screening

Clinical paper of the month

Prevalence and Severity of Undetected Manifest Glaucoma: Results from the Early Manifest Glaucoma Trial Screening

Author(s): Heijl A, Bengtsson B, Oskarsdottir SE. Lund University, Department of Clinical Sciences Malmö, Ophthalmology, Skåne University Hospital,...

June 30, 2013

Acetylcholinesterase inhibition promotes retinal vasoprotection and increases ocular blood flow in experimental glaucoma

Experimental Paper of the Month

Acetylcholinesterase inhibition promotes retinal vasoprotection and increases ocular blood flow in experimental glaucoma

Author(s): Almasieh M, Macintyre JN, Pouliot M, Casanova C, Vaucher E, Kelly ME, Di Polo A. Department of Pathology and Cell Biology and Groupe de...

June 30, 2013

The use of Ginkgo biloba may increase the risk of bleeding

Tip of the month

The use of Ginkgo biloba may increase the risk of bleeding

The Science behind the Tip Extracts of the leaves of the Asiatic tree Ginkgo biloba (GBE) provide protection against mitochondrial oxidative damage...

May 31, 2013

The eye and the heart

Clinical paper of the month

The eye and the heart

Author(s): Flammer J, Konieczka K, Bruno R M, Virdis A, Flammer A J, Taddei S The vasculature of the eye and the heart share several common...

May 31, 2013

Reduction in Blood Glutathione Levels Occurs Similarly in Patients with Primary-Open Angle or Normal Tension Glaucoma

Experimental Paper of the Month

Reduction in Blood Glutathione Levels Occurs Similarly in Patients with Primary-Open Angle or Normal Tension Glaucoma

Author(s): Gherghel D, Mroczkowska S, Qin L Vascular Research Laboratory, Ophthalmic Research Group, Aston University, School of Life and Health...

May 31, 2013

If surgery is required to control IOP in a patient with nanophthalmos, phacoemulsification with IOL implantation is a good option, but the complication rate is high

Tip of the month

If surgery is required to control IOP in a patient with nanophthalmos, phacoemulsification with IOL implantation is a good option, but the complication rate is high

The Science behind the Tip Nanophthalmos, small eye-big trouble, is a form of microophthalmos which is not accompanied by other congenital...

April 30, 2013

How Does Glaucoma Look?: Patient Perception of Visual Field Loss

Clinical paper of the month

How Does Glaucoma Look?: Patient Perception of Visual Field Loss

Author(s): Crabb DP, Smith ND, Glen FC, Burton R, Garway-Heath DF Department of Optometry and Visual Science, City University London, London,...

April 30, 2013

Tissue engineering the retinal ganglion cell nerve fiber layer

Experimental Paper of the Month

Tissue engineering the retinal ganglion cell nerve fiber layer

Author(s): Kador KE, Montero RB, Venugopalan P, Hertz J, Zindell AN, Valenzuela DA, Uddin MS, Lavik EB, Muller KJ, Andreopoulos FM, Goldberg JL...

April 30, 2013

Indefinite use of cycloplegics can be the last resort when surgery for malignant glaucoma has failed

Tip of the month

Indefinite use of cycloplegics can be the last resort when surgery for malignant glaucoma has failed

The Science behind the Tip Malignant glaucoma or aqueous misdirection is a rare but feared complication of anterior segment surgery. It occurs in...

March 31, 2013

Treatment Outcomes in Malignant Glaucoma

Clinical paper of the month

Treatment Outcomes in Malignant Glaucoma

Author(s): Dave P, Senthil S, Rao HL, Garudadri CS. L. V. Prasad Eye Institute, Hyderabad, India. PURPOSE: To report treatment outcomes in...

March 31, 2013

Discovery of novel human aquaporin-1 blockers

Experimental Paper of the Month

Discovery of novel human aquaporin-1 blockers

Author(s): Seeliger D, Zapater C, Krenc D, Haddoub R, Flitsch S, Beitz E, Cerdà J, de Groot BL. Human aquaporin-1 (hAQP1) is a water channel found...

March 31, 2013

Young men of European ancestry with angle-closure require thorough investigation

Tip of the month

Young men of European ancestry with angle-closure require thorough investigation

The Science behind the Tip Primary angle closure glaucoma is rare in younger white adults, with an estimated age specific prevalence of 0.02% for...

February 28, 2013

Protective effect of lipoic acid against oxidative stress is mediated by Keap1/Nrf2-dependent heme oxygenase-1 induction in the RGC-5 cell line

Experimental Paper of the Month

Protective effect of lipoic acid against oxidative stress is mediated by Keap1/Nrf2-dependent heme oxygenase-1 induction in the RGC-5 cell line

Author(s): Koriyama Y, Nakayama Y, Matsugo S, Kato S. Department of Molecular Neurobiology, Graduate School of Medicine. Electronic address:...

February 28, 2013

Balance control in glaucoma

Clinical paper of the month

Balance control in glaucoma

Author(s): Kotecha A, Richardson G, Chopra R, Fahy RT, Garway-Heath DF, Rubin GS Department of Visual Neuroscience, University College London (UCL)...

January 31, 2013

A new safety concern for glaucoma treatment demonstrated by mass spectrometry imaging of benzalkonium chloride distribution in the eye, an experimental study in rabbits

Experimental Paper of the Month

A new safety concern for glaucoma treatment demonstrated by mass spectrometry imaging of benzalkonium chloride distribution in the eye, an experimental study in rabbits

Author(s): Brignole-Baudouin F, Desbenoit N, Hamm G, Liang H, Both JP, Brunelle A, Fournier I, Guerineau V, Legouffe R, Stauber J, Touboul D,...

January 31, 2013

Intravitreal steroids should be used with caution in patients with glaucoma

Tip of the month

Intravitreal steroids should be used with caution in patients with glaucoma

The Science behind the Tip In recent years it has become common practice to inject steroids into the vitreous to reduce macular oedema or ocular...

December 31, 2012

Factors that influence standard automated perimetry test results in glaucoma: test reliability, technician experience, time of day, and season

Clinical paper of the month

Factors that influence standard automated perimetry test results in glaucoma: test reliability, technician experience, time of day, and season

Author(s): Junoy Montolio FG, Wesselink C, Gordijn M, Jansonius NM Department of Ophthalmology, University Medical Center Groningen, University of...

December 31, 2012

Dorsomedial/Perifornical hypothalamic stimulation increases intraocular pressure, intracranial pressure, and the translaminar pressure gradient

Experimental Paper of the Month

Dorsomedial/Perifornical hypothalamic stimulation increases intraocular pressure, intracranial pressure, and the translaminar pressure gradient

Author(s): Samuels BC, Hammes NM, Johnson PL, Shekhar A, McKinnon SJ, Allingham RR Eugene and Marilyn Glick Eye Institute, the. PURPOSE:...

December 31, 2012

Long-term application of benzalkonium chloride increases the risk of filtration surgery failure

Tip of the month

Long-term application of benzalkonium chloride increases the risk of filtration surgery failure

The Science behind the Tip Glaucoma medication solutions usually contain the preservative benzalkonium chloride (BAK) in concentrations varying...

November 30, 2012

Retinal Vessel Caliber Is Associated with the 10-year Incidence of Glaucoma: The Blue Mountains Eye Study

Clinical paper of the month

Retinal Vessel Caliber Is Associated with the 10-year Incidence of Glaucoma: The Blue Mountains Eye Study

Author(s): Kawasaki R, Wang JJ, Rochtchina E, Lee AJ, Wong TY, Mitchell P. Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital,...

November 30, 2012

Genome-wide association analyses identify three new susceptibility loci for primary angle closure glaucoma

Experimental Paper of the Month

Genome-wide association analyses identify three new susceptibility loci for primary angle closure glaucoma

Author(s): Vithana EN, Khor CC, Qiao C, Nongpiur ME, George R, Chen LJ, Do T, Abu-Amero K, Huang CK, Low S, Tajudin LS, Perera SA, Cheng CY, Xu L,...

November 30, 2012

In patients with pseudoexfoliation glaucoma, phacoemulsification with IOL implantation can result in a late, sustained reduction in intraocular pressure

Tip of the month

In patients with pseudoexfoliation glaucoma, phacoemulsification with IOL implantation can result in a late, sustained reduction in intraocular pressure

The Science behind the Tip Raised intraocular pressure (IOP) in an eye with pseudoexfoliation syndrome results from pigment and exfoliation...

October 31, 2012